A synthesis that will carry out the transformation in Solved Problem 21.8 but does not involve benzoyl chloride an an intermediate is to be proposed. Concept introduction: Carboxylic acid derivatives can be relatively easily interconverted provided the product is more stable (lower in the stability ladder) than the susbtrate. Conversion of a substrate lower on the stability ladder (more stable) to one higher on the ladder (less stable) is usually not feasible. Such syntheses must be carried out in a number of reaction steps, generally involving inorganic reagents. The least stable acid derivative is acid chloride, so the first step would be conversion of the stable substrate to acid chloride using an inorganic reagent like SOCl 2 . The acid chloride can then be relatively esily converted to any derivative, even one less stable than the starting compound.

Question

Want to see the full answer?

Answer 1

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.9P

Interpretation Introduction

Interpretation:

A synthesis that will carry out the transformation in Solved Problem 21.8 but does not involve benzoyl chloride an an intermediate is to be proposed.

Concept introduction:

Carboxylic acid derivatives can be relatively easily interconverted provided the product is more stable (lower in the stability ladder) than the susbtrate. Conversion of a substrate lower on the stability ladder (more stable) to one higher on the ladder (less stable) is usually not feasible. Such syntheses must be carried out in a number of reaction steps, generally involving inorganic reagents. The least stable acid derivative is acid chloride, so the first step would be conversion of the stable substrate to acid chloride using an inorganic reagent like SOCl2. The acid chloride can then be relatively esily converted to any derivative, even one less stable than the starting compound.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Draw the stepwise mechanism for the reactions

Part I. a) Draw reaction mechanism for the transformations of benzophenone to benzopinacol to benzopinaco lone b) Pinacol (2,3-dimethyl, 1-3-butanediol) on treatment w/ acid gives a mixture of pina colone (3,3-dimethyl-2-butanone) and 2, 3-dimethyl - 1,3-butadiene. Give reasonable mechanism the formation of the products For

3. The explosive decomposition of 2 mole of TNT (2,4,6-trinitrotoluene) is shown below: Assume the C(s) is soot-basically atomic carbon (although it isn't actually atomic carbon in real life). 2 CH3 H NO2 NO2 3N2 (g)+7CO (g) + 5H₂O (g) + 7C (s) H a. Use bond dissociation energies to calculate how much AU is for this reaction in kJ/mol.

Answer 2

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.9P

Interpretation Introduction

Interpretation:

A synthesis that will carry out the transformation in Solved Problem 21.8 but does not involve benzoyl chloride an an intermediate is to be proposed.

Concept introduction:

Carboxylic acid derivatives can be relatively easily interconverted provided the product is more stable (lower in the stability ladder) than the susbtrate. Conversion of a substrate lower on the stability ladder (more stable) to one higher on the ladder (less stable) is usually not feasible. Such syntheses must be carried out in a number of reaction steps, generally involving inorganic reagents. The least stable acid derivative is acid chloride, so the first step would be conversion of the stable substrate to acid chloride using an inorganic reagent like SOCl2. The acid chloride can then be relatively esily converted to any derivative, even one less stable than the starting compound.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 3

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.9P

Interpretation Introduction

Interpretation:

A synthesis that will carry out the transformation in Solved Problem 21.8 but does not involve benzoyl chloride an an intermediate is to be proposed.

Concept introduction:

Carboxylic acid derivatives can be relatively easily interconverted provided the product is more stable (lower in the stability ladder) than the susbtrate. Conversion of a substrate lower on the stability ladder (more stable) to one higher on the ladder (less stable) is usually not feasible. Such syntheses must be carried out in a number of reaction steps, generally involving inorganic reagents. The least stable acid derivative is acid chloride, so the first step would be conversion of the stable substrate to acid chloride using an inorganic reagent like SOCl2. The acid chloride can then be relatively esily converted to any derivative, even one less stable than the starting compound.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Answer 4

Question

Definition Definition Class of organic compounds that contain a carboxyl group ( - COOH ) and has a general formula R - COOH or R - CO 2 H , where R refers to the alkyl, alkenyl, aryl, or other groups. They can undergo different chemical reactions, such as acid-base reactions, esterification, and oxidation. These are essential components of living organisms, playing important roles in metabolic processes, signaling, and as pharmaceuticals.

Chapter 21, Problem 21.9P

Interpretation Introduction