Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 2, Problem 31P

A woman expressing a dominant phenotype is heterozy-gous (Dd) for the gene.

a. What is the probability that the dominant allele carried by the woman will be inherited by a grandchild?

b. What is the probability that two grandchildren of the woman who are first cousins to one another will each inherit the dominant allele?

c. Draw a pedigree that illustrates the transmission of the dominant trait from the grandmother to two of her grandchildren who are first cousins.

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Imagine that you are a clinical geneticist. Your colleague is an oncologist who wants your help explaining the basics of genetics to their patient, who will be undergoing genetic testing in the coming weeks for possible acute myeloid leukemia (AML) induced by the radiation she had several years ago for breast cancer. Write a 1,050- to 1,225-word memo to your colleague. Include the following in your memo: An explanation of the molecular structure of DNA and RNA, highlighting both similarities and differences  A description of the processes of transcription and translation An explanation of the differences between leading and lagging strands and how the DNA is replicated in each strand Reponses to the following common questions patients might ask about this type of genetic testing and genetic disorder: Does AML run in families? What genes are tested for?
Respond to the following in a minimum of 175 words: What are some potential consequences that could result if the processes of replication, transcription, and translation don’t function correctly? Provide an example of how you might explain these consequences in terms that patients might understand.

Chapter 2 Solutions

Genetic Analysis: An Integrated Approach (3rd Edition)

Ch. 2 - 11. Black skin color is dominant to pink skin...Ch. 2 - A male mouse with brown fur color is mated to two...Ch. 2 - 13. Figure 2.12 shows the results of Mendel’s...Ch. 2 - 14. An experienced goldfish breeder receives two...Ch. 2 - 15. The accompanying pedigree shows the...Ch. 2 - 16. A geneticist crosses a pure-breeding strain...Ch. 2 - Suppose an F1 plant from Problem 16 is crossed to...Ch. 2 - 18. In pea plants, the appearance of flowers along...Ch. 2 - 19. If two six-sided dice are rolled, what is the...Ch. 2 - Experimental Insight 2.1 describes data, collected...Ch. 2 - 21. The accompanying pedigree shows the...Ch. 2 - 22. The seeds in bush bean pods are each the...Ch. 2 - List all the different gametes that are possible...Ch. 2 - Organisms with the genotypes AABbCcDd and AaBbCcDd...Ch. 2 - 25. Blue moon beans produce beans that are either...Ch. 2 - In the fruit fly Drosophila, a rudimentary wing...Ch. 2 - In pea plants, plant height, seed shape, and seed...Ch. 2 - A variety of pea plant called Blue Persian...Ch. 2 - 29. In tomato plants, the production of red fruit...Ch. 2 - A male and a female are each heterozygous for both...Ch. 2 - A woman expressing a dominant phenotype is...Ch. 2 - Two parents who are each known to be carriers of...Ch. 2 - 33. An organism having the genotype AaBbCcDdEe is...Ch. 2 - 34. A man and a woman are each heterozygous...Ch. 2 - For a single dice roll, there is a 16 chance that...Ch. 2 - You have four guinea pigs for a genetic study. One...Ch. 2 - 37. Galactosemia is an autosomal recessive...Ch. 2 - Sweet yellow tomatoes with a pear shape bring a...Ch. 2 - A cross between a spicy variety of Capsicum annum...Ch. 2 - Alkaptonuria is an infrequent autosomal recessive...Ch. 2 - 41. Humans vary in many ways from one another....Ch. 2 - 42. In chickens, the presence of feathers on the...Ch. 2 - 43. A pure-breeding fruit fly with the...Ch. 2 - 44. Situs inversus is a congenital condition in...Ch. 2 - 45. Domestic dogs evolved from ancestral grey...Ch. 2 - Alleles of the IGF-1 gene in dogs, encoding...Ch. 2 - 47. The accompanying pedigree shows a family in...Ch. 2 - 48. A pea plant that has the genotype RrGgwwdd is...Ch. 2 - Go to the OMIM website...Ch. 2 - Prob. 50PCh. 2 - Prob. 51PCh. 2 - 52. In humans, the ability to bend the thumb...
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