Glutamate is converted into α- ketoglutarate by the reaction sequence shown below. The structure of the imine intermediate is to be shown and mechanisms for both steps are to be proposed. Concept introduction: Transfer of a hydride ion from the glutamate to NAD+ followed by the deprotonation of the intermediate formed will yield the imine. The attack of water on the protonated imine and subsequent deprotonation yield a carbinolamine intermediate. The intermediate on further reaction breaks to yield a ketone and amine /ammonia as products. To show: The structure of the imine intermediate formed when glutamate is converted into α- ketoglutarate by the reaction sequence shown below and to propose mechanisms for both steps.

Question

The table includes macrostates characterized by 4 energy levels (&) that are equally spaced but with different degrees of occupation. a) Calculate the energy of all the macrostates (in joules). See if they all have the same energy and number of particles. b) Calculate the macrostate that is most likely to exist. For this macrostate, show that the population of the levels is consistent with the Boltzmann distribution. macrostate 1 macrostate 2 macrostate 3 ε/k (K) Populations Populations Populations 300 5 3 4 200 7 9 8 100 15 17 16 0 33 31 32 DATO: k = 1,38×10-23 J K-1

Answer 1

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 19.SE, Problem 50MP

Interpretation Introduction

Interpretation:

Glutamate is converted into α- ketoglutarate by the reaction sequence shown below.

The structure of the imine intermediate is to be shown and mechanisms for both steps are to be proposed.

Concept introduction:

Transfer of a hydride ion from the glutamate to NAD+ followed by the deprotonation of the intermediate formed will yield the imine.

The attack of water on the protonated imine and subsequent deprotonation yield a carbinolamine intermediate. The intermediate on further reaction breaks to yield a ketone and amine/ammonia as products.

To show:

The structure of the imine intermediate formed when glutamate is converted into α- ketoglutarate by the reaction sequence shown below and to propose mechanisms for both steps.

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The table includes macrostates characterized by 4 energy levels (&) that are equally spaced but with different degrees of occupation. a) Calculate the energy of all the macrostates (in joules). See if they all have the same energy and number of particles. b) Calculate the macrostate that is most likely to exist. For this macrostate, show that the population of the levels is consistent with the Boltzmann distribution. macrostate 1 macrostate 2 macrostate 3 ε/k (K) Populations Populations Populations 300 5 3 4 200 7 9 8 100 15 17 16 0 33 31 32 DATO: k = 1,38×10-23 J K-1

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In an experiment, the viscosity of water was measured at different temperatures and the table was constructed from the data obtained. a) Calculate the activation energy of viscous flow (kJ/mol). b) Calculate the viscosity at 30°C. T/°C 0 20 40 60 80 η/cpoise 1,972 1,005 0,656 0,469 0,356

Answer 2

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 19.SE, Problem 50MP

Interpretation Introduction

Interpretation:

Glutamate is converted into α- ketoglutarate by the reaction sequence shown below.

The structure of the imine intermediate is to be shown and mechanisms for both steps are to be proposed.

Concept introduction:

Transfer of a hydride ion from the glutamate to NAD+ followed by the deprotonation of the intermediate formed will yield the imine.

The attack of water on the protonated imine and subsequent deprotonation yield a carbinolamine intermediate. The intermediate on further reaction breaks to yield a ketone and amine/ammonia as products.

To show:

The structure of the imine intermediate formed when glutamate is converted into α- ketoglutarate by the reaction sequence shown below and to propose mechanisms for both steps.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 3

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 19.SE, Problem 50MP

Interpretation Introduction

Interpretation:

Glutamate is converted into α- ketoglutarate by the reaction sequence shown below.

The structure of the imine intermediate is to be shown and mechanisms for both steps are to be proposed.

Concept introduction:

Transfer of a hydride ion from the glutamate to NAD+ followed by the deprotonation of the intermediate formed will yield the imine.

The attack of water on the protonated imine and subsequent deprotonation yield a carbinolamine intermediate. The intermediate on further reaction breaks to yield a ketone and amine/ammonia as products.

To show:

The structure of the imine intermediate formed when glutamate is converted into α- ketoglutarate by the reaction sequence shown below and to propose mechanisms for both steps.

Expert Solution & Answer

Trending nowThis is a popular solution!

See solution

Check out sample textbook solution

Answer 4

Question

Definition Definition Organic compounds that have a carbonyl group, C = O, as their functional group. The carbonyl group in ketones is placed somewhere in the middle of the molecular structure, which means, the C=O is attached to two alkyl groups or benzene rings. Just like all other homologous series, the naming of ketones is done using a common suffix “-one”. The general molecular formula is C n H 2n O. Functional group of a ketone

Chapter 19.SE, Problem 50MP

Interpretation Introduction