Diagnosis in the Desert
In the 1970s, archeologists unearthed a vast cemetery in the Atacama Desert of Chile. Because the Atacama is the driest desert on Earth, bodies over 800 years old were better preserved than might be expected. Some facial and brain tissues were mummified. The skulls of four women appeared as if the bone had been eaten, though it was obvious to the archeologists that the women had lived with the condition and died from other causes. It wasn’t until 2009 that scientists were able to solve the mystery of these skulls. Genetic analysis of tissue samples revealed that a flagellated protozoan had moved from facial lesions to the women’s skulls, slowly eating them away over a 20-year period.
- 1. What skin pathogen caused the disfigurement?
- 2. How did the women become infected?
- 3. If the women were infected today, what treatment would be given?
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Chapter 19 Solutions
EBK MICROBIOLOGY:W/DISEASES BY BODY...-
- "One of the symmetry breaking events in mouse gastrulation requires the amplification of Nodal on the side of the embryo opposite to the Anterior Visceral Endoderm (AVE). Describe one way by which Nodal gets amplified in this region." My understanding of this is that there are a few ways nodal is amplified though I'm not sure if this is specifically occurs on the opposite side of the AVE. 1. pronodal cleaved by protease -> active nodal 2. Nodal -> BMP4 -> Wnt-> nodal 3. Nodal-> Nodal, Fox1 binding site 4. BMP4 on outside-> nodal Are all of these occuring opposite to AVE?arrow_forwardIf four babies are born on a given day What is the chance all four will be girls? Use genetics lawsarrow_forwardExplain each punnet square results (genotypes and probabilities)arrow_forward
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- Plekhg5 functions in bottle cell formation, and Shroom3 functions in neural plate closure, yet the phenotype of injecting mRNA of each into the animal pole of a fertilized egg is very similar. What is the phenotype, and why is the phenotype so similar? Is the phenotype going to be that there is a disruption of the formation of the neural tube for both of these because bottle cell formation is necessary for the neural plate to fold in forming the neural tube and Shroom3 is further needed to close the neural plate? So since both Plekhg5 and Shroom3 are used in forming the neural tube, injecting the mRNA will just lead to neural tube deformity?arrow_forwardWhat are some medical issues or health trends that may have a direct link to the idea of keeping fat out of diets?arrow_forwardwhat did charles darwin do in sciencearrow_forward
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