Chapter 18.7, Problem 1Q

Consider the hydrolysis reactions of creatine phosphate and adenosine-5′-monophosphate.

Creatine Phosphate + H₂O → Creatine + HP_i

Δ_rG°’ = −43.3 KJ/mol-rxn

Adenosine-5′-Honophosphate + H₂O → Adenosine + HP_i

Δ_rG°’ = −9.2 KJ/mol-rxn

Which of the following combinations produces a reaction that is product-favored at equilibrium: for creatine phosphate to transfer phosphate to adenosine or for adenosine-5′-monophosphate to transfer phosphate to creatine?