PRIN.OF GENERAL,ORGANIC+BIOLOG.CHEM.
PRIN.OF GENERAL,ORGANIC+BIOLOG.CHEM.
2nd Edition
ISBN: 9781266811852
Author: SMITH
Publisher: MCG
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Chapter 18, Problem 18.33UKC

When a substrate is oxidized, is NAD+ oxidized or reduced? Is NAD+ an oxidizing agent or a reducing agent?

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2) There are many forms of cancer, all of which involve abnormal cell growth. The growth and production of cells, called cell proliferation, is known to involve an enzyme called protein farnesyltransferase (PFTase). It is thought that inhibitors pf PFTase may be useful as anticancer drugs. The following molecule showed moderate activity as a potential PFTase inhibitor. Draw all stereoisomers of this compound. HO OH
Considering rotation around the bond highlighted in red, draw the Newman projection for the most stable and least stable conformations when viewed down the red bond in the direction of the arrow. Part 1 of 2 H₁₂C H H Draw the Newman projection for the most stable conformation. Select a template to begin. Part 2 of 2 Draw the Newman projection for the least stable conformation. G 心
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