Genetics: From Genes to Genomes, 5th edition
5th Edition
ISBN: 9780073525310
Author: Leland H. Hartwell, Michael L. Goldberg, Janice A. Fischer, Leroy Hood, Charles F. Aquadro
Publisher: McGraw-Hill Education
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Chapter 17, Problem 14P
| a. | Diagram a knockin construct that could have been used to create the mouse model for achondroplasia shown in Fig. 17.12 (p. 588). |
| b. | Explain how TALENs could have been used to produce the same mice. |
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Chapter 17 Solutions
Genetics: From Genes to Genomes, 5th edition
Ch. 17 - Match each of the terms in the left column to the...Ch. 17 - Mice are usually gray, but a mouse geneticist has...Ch. 17 - Sometimes, genes transferred into the mouse genome...Ch. 17 - In mice, a group of so-called Hox genes encode...Ch. 17 - The fly eyes shown in Fig. 17.6 p. 580 are...Ch. 17 - Prob. 6PCh. 17 - Fish and other organisms that live in the Arctic...Ch. 17 - Prob. 8PCh. 17 - The first page of this chapter p. 575 shows a...Ch. 17 - The goal of the Knockout Mouse Project is to...
Ch. 17 - Prob. 11PCh. 17 - Recall that constructs used for floxing a gene...Ch. 17 - a. Which genome manipulation technique would you...Ch. 17 - a. Diagram a knockin construct that could have...Ch. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - A transcription factor Pax6 is required...Ch. 17 - Mouse models for human genetic diseases are...Ch. 17 - One way to determine where inside a cell a protein...Ch. 17 - Prob. 20PCh. 17 - Prob. 21PCh. 17 - Recall that Leber congenital amaurosis LCA, a form...Ch. 17 - One potential strategy for gene therapy to correct...
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