Chapter 17, Problem 13TYU

Summary Introduction

To explain: The pattern of Siamese cat’s fur pigmentation due to ‘temperature-sensitive’ mutation in the gene encoding dark fur pigment.

Concept introduction:

Siamese cats have unique fur pigmentation pattern known as ‘colorpoints’. The pattern includes dark ears, face, legs, and tail, while a creamy white shade is seen on the back and belly. They are partial albinos. This is caused due to a ‘temperature-sensitive’ mutation in the gene encoding tyrosinase enzyme required for the melanin production. It does not work at normal body temperatures.