Biology: Life on Earth with Physiology (11th Edition)
11th Edition
ISBN: 9780133923001
Author: Gerald Audesirk, Teresa Audesirk, Bruce E. Byers
Publisher: PEARSON
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Chapter 16.3, Problem 3TC
Microbiologists have discovered that alleles associated with antibiotic resistance are present in bacteria that live in soil, even in environments that are comparatively free of antibiotic pollution from human activities. Why are such alleles present (albeit at low levels) in bacterial populations? Conversely, if resistance alleles are beneficial, why are they rare in natural populations of bacteria?
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Escherichia coli (E. coli) is a bacterium normally found in the human gut. It is harmless and may actually be beneficial to the human digestive system. There is a pathogenic strain of E. coli that produces a toxin that can kill its human host. The two strains look very similar under the microscope. Comparison of their genomes reveals that the pathogenic strain lacks 528 genes found in the normal strain and has 1,387 genes not found in the not found in the normal strain.
Are the normal and pathogenic strains of E.coli separate species? Explain your answer.
A mutation occurs in a single bacterium that causes it to produce a new enzyme. This enzyme helps the bacterium process nutrients more efficiently, increasing the bacterium's odds of survival.
Every 30 minutes, the bacteria in the colony divide, passing their genes on to their offspring. Some bacteria survive, while others do not. Because resources are limited, the colony has a steady population of 114 bacteria.
The bacterial colony is shown below at three different time intervals.
Assume that the survival trend shown in the diagram continues. At 3.0 hours, the mutant bacteria will make up how many percent of the entire colony?
A newly-identified relative of Staphylococcus is causing great concern at the Center for Disease Control. It has been observed that some strains of this new bacterial species are resistant to multiple antibiotics used in clinical settings. Thanks to your bacterial genetic prowess, you are hired as part of a research team whose mission is to characterize this new species. It appears that at least three different antibiotic resistance genes have integrated onto the bacterial chromosome:
min+ = confers resistance to minocycline
cep+ = confers resistance to cephalexin
van+ = confers resistance to vancomycin
The following table shows the results of your experiments. Transformation of the recipient cells was conducted, using the DNA of the donor cells. You next selected for recipient cells that had undergone transformation by plating the transformed cells on media containing minocycline. This enabled you to select for min+ cells. The min+ cells were then replica plated onto media…
Chapter 16 Solutions
Biology: Life on Earth with Physiology (11th Edition)
Ch. 16.1 - define evolution in terms of concepts from...Ch. 16.1 - define equilibrium population and describe the...Ch. 16.2 - Evolution of a Menace The mutant alleles that...Ch. 16.2 - describe how mutation, gene flow, genetic drift,...Ch. 16.2 - A flu vaccination stimulates your immune system to...Ch. 16.2 - If it were true that mutations do occur in...Ch. 16.2 - Explain how the distribution of genotypes in...Ch. 16.2 - If a population grows large again after a...Ch. 16.2 - Prob. 4TCCh. 16.3 - describe why selection of phenotypes can affect...
Ch. 16.3 - A team of phys clans treated four patients with...Ch. 16.3 - If we studied a population of bighorn sheep and...Ch. 16.3 - explain how competition and predation influence...Ch. 16.3 - When selection is directional, is there any limit...Ch. 16.3 - Prob. 3CYLCh. 16.3 - Microbiologists have discovered that alleles...Ch. 16.3 - compare and contrast directional selection,...Ch. 16 - In North America, the average height of adult...Ch. 16 - The ______ provides a simple mathematical model...Ch. 16 - The alleles responsible for antibiotic resistance...Ch. 16 - What is a gene pool? How would you determine the...Ch. 16 - By the 1940s, the whooping crane population had...Ch. 16 - Different versions of the same gene are called...Ch. 16 - Stabilizing selection on a trait tends to a. make...Ch. 16 - Define equilibrium population. Outline the...Ch. 16 - An organisms ______ refers to the specific alleles...Ch. 16 - An adaptation is a. any trait that arises from a...Ch. 16 - How does population size affect the likelihood of...Ch. 16 - A random form of evolution is called ________....Ch. 16 - Which of the following statements about mutations...Ch. 16 - If you measured the allele frequencies of a gene...Ch. 16 - Competition is most Intense between members of...Ch. 16 - Genetic drift occurs a. when different phenotypes...Ch. 16 - People like to say that you cant prove a negative....Ch. 16 - The evolutionary fitness of an organism is...Ch. 16 - Describe the three ways in which natural selection...Ch. 16 - What is sexual selection? How is sexual selection...
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- Discuss the following statement: “mobile genetic elements are parasites. They are harmful to the host organism and therefore place it at an evolutionary disadvantage.”arrow_forwardYou have isolated a strain of E.coli that is resistant to penicillin,streptomycin,chloramphenicol and tetracycline. You also observe that when you mix this strain with a strain that is sensitive to all four antibiotics, the new strain becomes resistant to streptomycin,penicillin and chloramphenicol but not tetracycline. Explain how this is so?arrow_forwardPrice et al. (1999. J. Bacteriol. 181: 2358–2362) conducted a genetic study of the toxin transport protein (PA) of Bacillus anthracis, the bacterium that causes anthrax in humans. Within the 2294-nucleotide gene in 26 strains they identified five point mutations—two missense and three synonyms—among different isolates. Necropsy samples from an anthrax outbreak in 1979 revealed a novel missense mutation and five unique nucleotide changes among ten victims. The authors concluded that these data indicate little or no horizontal transfer between different B. anthracis strains. (a) Which types of nucleotide changes (missense or synonyms) cause amino acid changes? (b) What is meant by horizontal transfer? (c) On what basis did the authors conclude that evidence of horizontal transfer is absent from their data?arrow_forward
- This is a research article title "On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient". Full article text: Hermsen, R., Deris, J. B., & Hwa, T. (2012). On the rapidity of antibiotic resistance evolution facilitated by a concentration gradient. Proceedings of the National Academy of Sciences, 109(27), 10775–10780. doi:10.1073/pnas.1117716109 QUESTION: What are your thoughts in the article's title? Discuss you answer in Biology manner.arrow_forwardTwo mutations that affect plaque morphology in phages (a− and b −) have been isolated. Phages carrying both mutations (a− b−) are mixed with wild-type phages (a+ b+) and added to a culture of bacterial cells. Once the phages have infected and lysed the bacteria, samples of the phage lysate are collected and cultured on plated bacteria. The following numbers of plaques are observed: Plaque phenotype Number a+ b+ 2043 a+ b− 320 a− b+ 357 a− b− 2134 What is the frequency of recombination between the a and b genes?arrow_forwardA mutation occurs in a single bacterium that causes it to produce a new enzyme. This enzyme helps the bacterium process nutrients more efficiently, increasing the bacterium's odds of survival. Every 30 minutes, the bacteria in the colony divide, passing their genes on to their offspring. Some bacteria survive, while others do not. Because resources are limited, the colony has a steady population of 114 bacteria. The bacterial colony is shown below at three different time intervals. The picture would be here: Assume that the survival trend shown in the diagram continues. At 3.0 hours, the mutant bacteria will make up _____ percent of the entire colony.arrow_forward
- With the technique of interrupted mating four Hfr strains were tested for the sequence in which they transmitted a number of different genes to an F strain. Each Hfr strain was found to transmit its genes is a unique sequence, as shown in the accompanying table. What is the gene sequence in the original strain from which these Hfr strains were derived?arrow_forwardType S Streptococcus pneumoniae bacterium is lethal and will kill its host. If heat inactivated the S strain dies and becomes nonlethal. Type R Streptococcus pneumoniae is a nonvirulent strain of bacteria. What would occur if one were to inject both the R strain and heat-killed S strains into a host organism such as the mouse? The R strain would be transformed into the virulent S strain and kill the host. Neither the S nor the R strain would change. The R strain would be transformed into the virulent S strain and not affect the host. The S strain would be transformed into the nonvirulent R strain and not affect the host The S strain would be transformed into the nonvirulent R strain and kill the host.arrow_forwardPenicillin was first used in the 1940s to treat gonorrhea infections produced by the bacterium Neisseria gonorrhoeae. In 1984, according to the CDC, fewer than 1% of gonorrhea infections were caused by penicillin-resistant N. gonorrhoeae. By 1990, more than 10% of cases were penicillin resistant and a few years later the level of resistance was 95%. Explain the various ways this resistance could be spread among the cells. Could this resistance pass to other infectious bacteria from N. gonorrhoeae?arrow_forward
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