To determine the amount of energy, in terms of ATP consumption expended in the formation of a molecule of urea from ammonium ion and oxaloacetate. Concept introduction: Urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. It converts toxic ammonium ion to urea which is then excreted from the body in urine. Urea cycle constitutes 4 steps. In step 1 carbamoyl phosphate transfers its carbamoyl group to ornithine to produce citrulline. Citrulline then condenses with aspartate in the second step to form argininosuccinate which then cleaves in the third step to form arginine and fumarate. In the final step, arginine reacts with water to produce urea.

Question

You are trying to decide if there is a single reagent you can add that will make the following synthesis possible without any other major side products: xi 1. ☑ 2. H₂O хе i Draw the missing reagent X you think will make this synthesis work in the drawing area below. If there is no reagent that will make your desired product in good yield or without complications, just check the box under the drawing area and leave it blank. Click and drag to start drawing a structure. There is no reagent that will make this synthesis work without complications. : ☐ S ☐

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Chapter 15, Problem 15.69EP

Interpretation Introduction

Interpretation: To determine the amount of energy, in terms of ATP consumption expended in the formation of a molecule of urea from ammonium ion and oxaloacetate.

Concept introduction: Urea cycle is a cyclic biochemical pathway that involves the production of urea using ammonium ions and aspartate molecules as nitrogen sources. It converts toxic ammonium ion to urea which is then excreted from the body in urine.

Urea cycle constitutes 4 steps. In step 1 carbamoyl phosphate transfers its carbamoyl group to ornithine to produce citrulline. Citrulline then condenses with aspartate in the second step to form argininosuccinate which then cleaves in the third step to form arginine and fumarate. In the final step, arginine reacts with water to produce urea.

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