Study Guide for Campbell Biology
Study Guide for Campbell Biology
11th Edition
ISBN: 9780134443775
Author: Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Jane B. Reece, Martha R. Taylor, Michael A. Pollock
Publisher: PEARSON
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Chapter 15, Problem 13TYK

Genomic imprinting

  1. a. explains cases in which the phenotypic effect of an allele depends on the sex of the parent from whom that allele is inherited.
  2. b. may involve the silencing of an allele by methylation such that offspring inherit only one active copy of a gene.
  3. c. occurs more often in females because of the larger maternal contribution of cytoplasm.
  4. d. involves both a and b.
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In genetic maternal effect, the phenotype of the individual is determined by which of these statements? A. The sex of the parent who transmits the gene B. The nuclear genotype of the maternal parent C. The sex of the individual with only one sex able to express the phenotype D. Cytoplasmic genes usually located in the mitochondria E. A combination of environmental factors and the genotype of the individual
A. Deletion of the SOX9 gene leads to sex reversal resulting in a person with karyotype 46XY being phenotypically    Explain the genetic basis for this.    B. Describe what would happen to the phenotype of a male with a mutation in the gene encoding SF1? Explain your answer.
Imagine a scenario in which prenatal testing of a human female fetus indicates that the baby will have a normal XX karyotype but is heterozygous for a mutation that inactivates the Xist promoter.  Allele “Xr” represents the mutated version of the Xist promoter, and “XR” represents the normal version of the Xist promoter. How will this mutation affect the process of X inactivation?A. "X inactivation will still be random with both mutant and normal X chromosomes being randomly inactivated" B. "The chromosome with the mutant Xist promoter will always be active" C. "The chromosome with the mutant Xist promoter will always be inactivated" D. "The normal X chromosome (no mutation in Xist) will always be active" E. "The normal X chromosome (no mutation in Xist) will always be inactivated"
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