Â To review: An activation of both intrinsic and extrinsic pathways by cut in the skin. Â Introduction: Coagulation,Â alsoÂ knownÂ asÂ bloodÂ clotting,Â isÂ theÂ processÂ throughÂ whichÂ bloodÂ changesÂ fromÂ liquidÂ toÂ gelÂ toÂ makeÂ upÂ aÂ bloodÂ clot. TheÂ coagulationÂ mechanism involves platelet activation, adhesion, andÂ aggregation,Â asÂ wellÂ asÂ fibrinÂ depositionÂ andÂ maturation. Coagulation includes bothÂ a component of the cell (platelet) and aÂ proteinÂ (coagulationÂ factor)Â inÂ allÂ mammals. Â

Question

Want to see the full answer?

Answer 1

Question

Chapter 13, Problem 26RA

Summary Introduction

Â

To review:

An activation of both intrinsic and extrinsic pathways by cut in the skin.

Â

Introduction:

Coagulation,Â alsoÂ knownÂ asÂ bloodÂ clotting,Â isÂ theÂ processÂ throughÂ whichÂ bloodÂ changesÂ fromÂ liquidÂ toÂ gelÂ toÂ makeÂ upÂ aÂ bloodÂ clot. TheÂ coagulationÂ mechanism involves platelet activation, adhesion, andÂ aggregation,Â asÂ wellÂ asÂ fibrinÂ depositionÂ andÂ maturation. Coagulation includes bothÂ a component of the cell (platelet)

and aÂ proteinÂ (coagulationÂ factor)Â inÂ allÂ mammals.

Â

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Biopharmaceutics and Pharmacokinetics:Two-Compartment Model Instant Absorption Questions SHOW ALL WORK, including equation used, variables used and each step to your solution, report your regression lines and axes names (with units if appropriate) :Calculate a-q a) B1, b) B2, c) hybrid rate constant (1) d) hybrid rate constant (2) e) t1/2,dist f) t1/2,elim g) k10 h) k12 i) k21 j) initial concentration (C0) k) central compartment volume (V1) l) steady-state volume (Vss) m) clearance (CL) AUC (0→10 min) using trapezoidal rule n) AUC (20→30 min) using trapezoidal rule o) AUCtail (AUC360→∞) p) total AUC (using short cut method) q) volume from AUC (VAUC)

Glitazones reduce insulin resistance by binding to a transcription factor in adipocytes, thereby reducing thesecretion of fatty acids. Glitazones are taken orally (in pill form). Using pharmacokinetic modeling, deriveequations to describe how the concentration of glitazones varies in the plasma as a function of time. Yourequations should be of the form: dCglitazone /dt = something, or dMglitazone /dt = something. Your model shouldinclude three compartments: the gut, the plasma, and the fatty tissues. Make sure to include a diagram thatillustrates your thinking, state all assumptions, and define your variables. Do not solve the equations.

Case Study—Ella Review the case study and then answer Parts A through F. Ella has a family history of diabetes. She wants to follow a healthful eating pattern that can lower her risk for developing this condition. Her dietitian recommends a goal of 450 to 600 kcal per meal and advises Ella to follow the Acceptable Macronutrient Distribution Range (AMDR) for carbohydrates and the Dietary Guidelines for Americans 2015-2020, which recommend limiting added sugar. She also recommends that Ella choose whole grains rather than processed grains. Ella decides to pack a lunch to take to work every day. This morning she’s making a sandwich for her lunch. Categories of Sandwich Options (Top of the screen) Breads Spreads Cheeses Vegetables Proteins Specific food items to select White Bread 6-inches Honey Mustard Provolone LettuceTomatoBell Peppers Turkey Part A - Reading Nutrition Facts Panels for Total Kilocalories How many total kilocalories are in Ella’s sandwich? _____…