Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 12, Problem 3NST
If a human nucleus is 10 μm in diameter, and it must hold as much as 2 m of DNA, which is complexed into nucleosomes that during full extension are 11 nm in diameter, what percentage of the volume of the nucleus is occupied by the genetic material?
HINT: This problem asks you to make some numerical calculations in order to see just how “filled” the eukaryotic nucleus is with a diploid amount of DNA. The key to its solution is the use of the formula V = (4/3)πr3, which calculates the volume of a sphere.
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If a human nucleus is 10 mm in diameter, and it must hold as much as 2 m of DNA, which is complexed into nucleosomes that during full extension are 11 nm in diameter, what percentage of the volume of the nucleus does the genetic material occupy?
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Chapter 12 Solutions
Concepts of Genetics (12th Edition)
Ch. 12 - In bacteriophages and bacteria, the DNA is almost...Ch. 12 - After salivary gland cells from Drosophila are...Ch. 12 - If a human nucleus is 10 m in diameter, and it...Ch. 12 - Roberts syndrome is a rare inherited disorder...Ch. 12 - Prob. 2CSCh. 12 - Roberts syndrome is a rare inherited disorder...Ch. 12 - HOW DO WE KNOW? In this chapter, we focused on how...Ch. 12 - CONCEPT QUESTION Review the Chapter Concepts list...Ch. 12 - Contrast the size of the single chromosome in...Ch. 12 - Describe the structure of giant polytene...
Ch. 12 - What genetic process is occurring in a puff of a...Ch. 12 - During what genetic process are lampbrush...Ch. 12 - Why might we predict that the organization of...Ch. 12 - Describe the sequence of research findings that...Ch. 12 - Describe the molecular composition and arrangement...Ch. 12 - Describe the transitions that occur as nucleosomes...Ch. 12 - Provide a comprehensive definition of...Ch. 12 - Mammals contain a diploid genome consisting of at...Ch. 12 - Assume that a viral DNA molecule is a 50-m-long...Ch. 12 - How many base pairs are in a molecule of phage T2...Ch. 12 - Examples of histone modifications are acetylation...Ch. 12 - Contrast the structure of SINE and LINE DNA...Ch. 12 - Variable number tandem repeats (VNTRs) are...Ch. 12 - It has been shown that infectious agents such as...Ch. 12 - Cancer can be defined as an abnormal proliferation...Ch. 12 - In a study of Drosophila, two normally active...Ch. 12 - Prob. 21ESPCh. 12 - An article entitled Nucleosome Positioning at the...Ch. 12 - Prob. 23ESPCh. 12 - Following is a diagram of the general structure of...Ch. 12 - Microsatellites are currently exploited as markers...Ch. 12 - At the end of the short arm of human chromosome 16...
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- Discuss the levels of chromosomal organization with reference to the following terms: a. nucleotide b. DNA double helix c. histones d. nucleosomes e. chromatinarrow_forwardWhat difference exists between the compaction of chromosomes during metaphase versus interphase? Give at least one reason why this difference may be necessary.arrow_forwardThe picture below depicts electron micrographs of the major levels of chromatin structure. Match each of the listed conditions with the most likely levels of chromatin structure under that condition.arrow_forward
- Consider the figure beow, which depicts chromatin within the neucleus of a eukaryotic cell. nucleus O The letter A indicates regions of a single chromosome which are not expressed, and the letter B indicates regions of a single chromosome which are expressed. O Both answer choice A and answer choice B are correct. The letter A indicates regions of a single chromosome which are condensed and attached to the nuclear lamina, and the letter B indicates regions of a single chromosome which are partially decondensed. O Answer choices A, B and C are all correct. O The letter A represents repressed TADS, and the letter B represents active TADS.arrow_forwardIn all cells, microtubules nucleate from the centrosome and then become stabilized or collapse. What feature of microtubules contributes to this phenomenon?arrow_forwardIn the tracking chromosomal DNA movement through mitosis experiment, how many chromosomes did each of your daughter cells contain? Why is it important for each daughter cell to contain information identical to the parent cell? How often do human skin cells divide? Why might that be? Compare this rate to how frequently human neurons divide. What do you notice?arrow_forward
- Give only typing answer with explanation and conclusion Your analysis has identified that this new organism has same chromosomal structure as that of eukaryotes on earth. However, the average length of linker DNA of the new organism is 100 bp. If the haploid genome of the new organism has a size 6 billion bp, how many nucleosomes will be in this new organism?arrow_forwardA small amount if cytoplasm isolated from a mitotic cell is injected into an unfertilized frog oocyte, causing the oocyte to enter M phase. A sample of the injected cytoplasm is then taken and injected into a second oocyte, causing this cell also to enter the M phase. this process is repeated many times until essentially, none of the original protein samples remains, and yet, cytoplasm taken from the last in the series on injected oocytes is still able to trigger entry into the M phase with undiminished efficiency. Explain this remarkable observation.arrow_forwardWhat materials provide the substance of a densely staining chromosomes present during mitosis?arrow_forward
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