Concepts of Genetics (12th Edition)
Concepts of Genetics (12th Edition)
12th Edition
ISBN: 9780134604718
Author: William S. Klug, Michael R. Cummings, Charlotte A. Spencer, Michael A. Palladino, Darrell Killian
Publisher: PEARSON
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Chapter 12, Problem 3NST

If a human nucleus is 10 μm in diameter, and it must hold as much as 2 m of DNA, which is complexed into nucleosomes that during full extension are 11 nm in diameter, what percentage of the volume of the nucleus is occupied by the genetic material?

HINT: This problem asks you to make some numerical calculations in order to see just how “filled” the eukaryotic nucleus is with a diploid amount of DNA. The key to its solution is the use of the formula V = (4/3)πr3, which calculates the volume of a sphere.

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Concepts of Genetics (12th Edition)

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