Chapter 12, Problem 12.73P

Interpretation Introduction

Interpretation: Synthesis of $\left(3R,4S\right)\text{-3, 4-dichlorohexane}$ from acetylene and other required reagents is to be devised.

Concept introduction: Grignard reagents are organometallic compounds which are prepared using alkyl halides in presence of magnesium metal in dry ether. These reagents act as strong nucleophiles and bases.

The addition of ${\text{H}}_{\text{2}}$ in presence of catalyst is known as catalytic hydrogenation reaction. Lindlar catalyst consists of palladium deposited on calcium carbonate which is poisoned or deactivated by lead or sulfur. In presence of Lindlar catalyst, alkyne is reduced to $cis\text{-alkene}$.