Chapter 12, Problem 12.61P

Interpretation Introduction

Interpretation: Synthesis of the muscalure from acetylene and other required reagents is to be devised.

Concept introduction: Terminal alkynes can be converted into internal alkynes by forming new $\text{C}-\text{C}$ bond. This bond is formed by treatment of alkyne with strong base and alkyl halide.

The addition of ${\text{H}}_{\text{2}}$ in presence of catalyst is known as catalytic hydrogenation reaction. Lindlar catalyst consists of palladium deposited on calcium carbonate which is poisoned or deactivated by lead or sulfur. In presence of Lindlar catalyst, alkyne is reduced to $cis\text{-alkene}$.