Microbiology: A Systems Approach
4th Edition
ISBN: 9780073402437
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Textbook Question
Chapter 11.3, Problem 21AYP
Discuss the advantages and disadvantages of
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a. What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent.
b. What will happen to elimination of the drug in the previous question if the system is saturated? explain and show any math involved
If you wanted to reduce the difference between peak and trough levels that occur with repeated administration of a drug, how would you adjust the dose and dose interval without changing the plateau concentration (plateau is the average of peak and trough levels)? Select your answers for both dose and interval. Hint: It may be helpful to think about this problem using an example such as food. How would you eat if you wanted to maintain very steady hunger/satiety levels without changing your total caloric intake?
Options:
A. Dose; Increase dose
B. Dose; Decrease dose
C. Dose; Do not change dose
D. Interval; Increase the interval between doses (give the drug less frequently)
E. Interval; Decrease the interval between doses (give the drug more frequently)
F. Interval; Do not change the interval
What percentage of a drug is eliminated after 4 half-lives? Please round to the nearest percent. Show the math
Chapter 11 Solutions
Microbiology: A Systems Approach
Ch. 11.1 - Distinguish among the terms sterilization,...Ch. 11.1 - Prob. 2AYPCh. 11.1 - Prob. 3AYPCh. 11.1 - Name four categories of cellular targets for...Ch. 11.2 - Prob. 5AYPCh. 11.2 - Prob. 6AYPCh. 11.2 - Define thermal death time and thermal death point,...Ch. 11.2 - Prob. 8AYPCh. 11.2 - Prob. 9AYPCh. 11.2 - Identify advantages and disadvantages of cold...
Ch. 11.2 - Differentiate between the two types of radiation...Ch. 11.2 - Prob. 12AYPCh. 11.2 - Prob. 13AYPCh. 11.3 - Prob. 2CFCh. 11.3 - Name the desirable characteristics of chemical...Ch. 11.3 - Discuss several different halogen agents and their...Ch. 11.3 - List advantages and disadvantages to the use of...Ch. 11.3 - Explain the mode of action of alcohols and their...Ch. 11.3 - Prob. 18AYPCh. 11.3 - Define the term surfactant, and explain this...Ch. 11.3 - Identify examples of some heavy metal control...Ch. 11.3 - Discuss the advantages and disadvantages of...Ch. 11.3 - Prob. 22AYPCh. 11 - Prob. 1CFCh. 11 - Microbial control methods that kill/destroy...Ch. 11 - Sanitization is a process by which a. the...Ch. 11 - Prob. 3MCQCh. 11 - Prob. 4MCQCh. 11 - Prob. 5MCQCh. 11 - The primary mode of action of nonionizing...Ch. 11 - The most practical method of disinfecting...Ch. 11 - A chemical with sporicidal properties is a....Ch. 11 - Prob. 9MCQCh. 11 - Detergents are a. high-level germicides. b....Ch. 11 - Prob. 11TFCh. 11 - Prob. 12TFCh. 11 - Prob. 13TFCh. 11 - Prob. 14TFCh. 11 - Prob. 15TFCh. 11 - Prob. 1CTQCh. 11 - Prob. 2CTQCh. 11 - a.Precisely what is microbial death? b.Why does a...Ch. 11 - Prob. 4CTQCh. 11 - Prob. 5CTQCh. 11 - Prob. 6CTQCh. 11 - Prob. 7CTQCh. 11 - Prob. 8CTQCh. 11 - Tissue transplantation is a procedure that saves...Ch. 11 - Conduct additional research on the use of...Ch. 11 - Prob. 1CCCh. 11 - Prob. 2CCCh. 11 - Prob. 3CCCh. 11 - From chapter 2, figure 2.20. Study this...Ch. 11 - Prob. 2VCCh. 11 - Using the words that follow, please create a...
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