Genetics: From Genes to Genomes
6th Edition
ISBN: 9781259700903
Author: Leland Hartwell Dr., Michael L. Goldberg Professor Dr., Janice Fischer, Leroy Hood Dr.
Publisher: McGraw-Hill Education
expand_more
expand_more
format_list_bulleted
Concept explainers
Textbook Question
Chapter 11, Problem 8P
Humans and gorillas last shared a common ancestor about 10 million years ago. Humans and chimps last shared a common ancestor about 6 million years ago. The table that follows shows the corresponding genomic region from two gorilla gametes, three chimpanzee gametes, and three human gametes.
a. | Draw a cladogram similar to that in Fig. 11.6b to show the evolutionary relationships among these three species. |
b. | The data reveal six polymorphisms among these eight genomes, at positions 2 (A or G), 3 (A or T), 4 (G or T), 7 (C or T), 8 (C or T), and 9 (G or T). On your cladogram, indicate approximately when the mutations that produced each of these polymorphisms occurred. For each allele, state whether it is ancestral, derived, or that you can’t tell. |
c. | Infer the sequences in (i) the last common ancestor of humans and chimpanzees, and (ii) the last common ancestor of all three species. Use a question mark (?) to represent any uncertainty. |
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solutionStudents have asked these similar questions
Once nuclear DNA sequencing became fast and able to handle sequencing ancient DNA, living humans were found to have some Neanderthal genes. Is this finding clear evidence that some early modern humans did indeed hybridize with Neanderthals? Why?
A. What is the wild progenitor of maize and where is it found?
B. George Beadle concluded that this plant was the likely ancestor of maize (corn) even though the two plants appear very different. What evidence did Dr. Beadle collect that led to his conclusion?
C. How long ago was maize domesticated and what evidence was utilized to determine this?
D. Dr. Doebley and his team compared the DNA sequence of maize to that of a number of teosinte varieties from throughout Mexico. What did their analysis reveal?
Which of the following best explains the number of similarities between the amino acid sequences of the Drosophila Hedgehog protein and the Chicken Indian Hedgehog protein?
O A.
The Drosophila hedgehog gene evolved from hedgehogs, which are distantly related to birds.
O B.
Both genes evolved from a gene present in the last common ancestor of Drosphila and chickens, and the number of differences reflects the amount of time that has elapsed during the evolution of these two lineages.
a During the evolution of Drosophila and chickens, a hedgehog like gene arose independently in each lineage, then the gene that arose in chickens diversified.
A These genes are unrelated, and the fact that they are similar is only because the proteins need to have similar biochemical properties.
They are unrelated because chickens don't have segments and Drosophila larvae don't have limb buds.
Chapter 11 Solutions
Genetics: From Genes to Genomes
Ch. 11 - Choose the phrase from the right column that best...Ch. 11 - Would you characterize the pattern of inheritance...Ch. 11 - Would you be more likely to find single nucleotide...Ch. 11 - A recent estimate of the rate of base...Ch. 11 - If you examine Fig. 11.5 closely, you will note...Ch. 11 - Approximately 50 million SNPs have thus far been...Ch. 11 - Mutations at simple sequence repeat SSR loci occur...Ch. 11 - Humans and gorillas last shared a common ancestor...Ch. 11 - In 2015, an international team of scientists...Ch. 11 - Using PCR, you want to amplify an approximately 1...
Ch. 11 - Prob. 11PCh. 11 - The previous problem raises several interesting...Ch. 11 - You want to make a recombinant DNA in which a PCR...Ch. 11 - You sequence a PCR product amplified from a...Ch. 11 - Prob. 15PCh. 11 - The trinucleotide repeat region of the Huntington...Ch. 11 - Sperm samples were taken from two men just...Ch. 11 - Prob. 18PCh. 11 - a. It is possible to perform DNA fingerprinting...Ch. 11 - On July 17, 1918, Tsar Nicholas II; his wife the...Ch. 11 - The figure that follows shows DNA fingerprint...Ch. 11 - Microarrays were used to determine the genotypes...Ch. 11 - A partial sequence of the wild-type HbA allele is...Ch. 11 - a. In Fig. 11.17b, PCR is performed to amplify...Ch. 11 - The following figure shows a partial microarray...Ch. 11 - Scientists were surprised to discover recently...Ch. 11 - The microarray shown in Problem 25 analyzes...Ch. 11 - The figure that follows shows the pedigree of a...Ch. 11 - One of the difficulties faced by human geneticists...Ch. 11 - Now consider a mating between consanguineous...Ch. 11 - The pedigree shown in Fig. 11.22 was crucial to...Ch. 11 - You have identified a SNP marker that in one large...Ch. 11 - The pedigrees indicated here were obtained with...Ch. 11 - Approximately 3 of the population carries a mutant...Ch. 11 - The drug ivacaftor has recently been developed to...Ch. 11 - In the high-throughput DNA sequencing protocol...Ch. 11 - A researcher sequences the whole exome of a...Ch. 11 - As explained in the text, the cause of many...Ch. 11 - Figure 11.26 portrayed the analysis of Miller...Ch. 11 - A research paper published in the summer of 2012...Ch. 11 - Table 11.2 and Fig. 11.27 together portray the...Ch. 11 - The human RefSeq of the entire first exon of a...Ch. 11 - Mutations in the HPRT1 gene in humans result in at...Ch. 11 - Prob. 44P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Since nucleotide sequences are more variable than amino acid sequences, you’ll use GAPDH nucleotide sequences to compare across the six taxa you’re analyzing. Suppose that you used BLAST to align all possible pairs of GAPDH sequences among lancelet, lamprey, bass, frog, turtle, and leopard. You would be able to construct the following table showing the percent similarity values across all six taxa. Leopard Turtle Frog Bass Lamprey Lancelet Leopard 100% 83% 80% 81% 76% 74% Turtle – 100% 79% 79% 74% 72% Frog – – 100% 79% 74% 71% Bass – – – 100% 77% 74% Lamprey – – – – 100% 73% Lancelet – – – – – 100% Now you can use this data (similarly to how you used the data in the character table) to build a phylogenetic tree. The distance between species in a tree is directly related to the amount of similarity between their gene sequences. For instance, two species will be closer together if the amount of similarity is high, or far apart if the amount of similarity is low. Which…arrow_forwardUsing the picture below of the triangles and pentagon answer this question: 2.a) Identify potential Synapomorphies aka "Shared Derived Characters": To pick informative characters, look for things that are shared between two or more members of the ingroup. Give a DETAILED description of each of the characters you are going to use. This is important, as often two characters are very similar (see example on the next page). Remember, they should be binary (i.e., one of two states--black or white, two eyes or four eyes). They should not be subjective (i.e., long vs. short). You can always identify the ancestral state of your character by asking if the outgroup shows the character of interest. Answer this completely and correctly. Do not use previous answers/versions of answers.arrow_forwardIf 4% of human and chimpanzee DNA differs, how many base pairs differ between the two species? (Hint: The human genome contains 3.2 billion base pairs of DNA.) Is this a large or a small difference? Explain your reasoning.arrow_forward
- a) Examine the pedigree to the right. How many individuals have the same mitochondrial DNA as individual A? (Do not count individual A.) b) From the same pedigree, how many individuals have the same mitochondrial DNA as individual B? (Do not count individual B.)arrow_forwardYou are interested if whether several genes of a certain species of beetle assort independently. So, you conduct several generations of matings, and after you have collected all your data, you are ready to analyze your results. You conduct a Chi2 test to test your hypothesis. You have 6 groups and calculate a Chi? = 13.22. Given that the critical value at 0.05 level of %3D significance = 11.07 at df = 5, %3D (A) State your null hypothesis. (B) Should you accept or reject your null hypothesis? (C) Why did you arrive your decision in (B)?arrow_forwardThe SCAM data for positions V51C and Y96C are different to the other datasets. Describe how the data for these positions are different to the other positions. In each case, explain what the structural basis of these differences may be.arrow_forward
- A population of diploid, outbreeding, sexuall-reproducing rodents, population A, lives on a small island. The population consists of 100,000 individuals a)Are all of the individuals of population A genetically identical? Answer yes or no b) A volcanic eruption carves the island into two populations (A1 and A2, 50,000 individuals each). The rodents cannot cross the lava. Immediately after the eruption, you take 100 individuals from each of populations A1 and A2. You are shown a DNA sequence chosen at random from the total pool of 200 sequences; can you tell which population, A1 or A2, it comes from? Answer yes or no. c)How would you determine whether or not individuals from A1 and A2 are reproductively isolated from each other?arrow_forwardLength of snakes can vary between 0.8m and 2.3 m long. In a large population of snakes there were just 2 of 2.3m length out of 560 snakes. How many genes are involved in determining this character?arrow_forwardHumans carry a variety of non-functional genetic sequences, called processed pseudogenes, in their DNA. we can estimate how long ago these sequences first appeared in the genomes of our ancestors. In humans, processed pseudogenes include the three options below which would be the least widespread among other primate species a. alpha-enolase psi1 (11 million years old) b. AS PSI 7 (16 million years old) c. CALM II PSI3 (36 million years old)arrow_forward
- Match the numbered concepts to the lettered facts. Explain why each pair is the best match. (1) Gene Duplication (2) Molecular Clock (3) Pseudogene (4) SINES and LINES a. Different kinds of globin chains arose over time including myoglobin, alpha globin, beta globin 1, delta globin, and beta globin 2.b. The two human beta globin genes, 1 and 2, differ at 20 base pair sites; only beta gene 1 produces a functional protein.c. In human hemoglobin, the delta polypeptide chain differs by 39 amino acid sites vs. the beta chain.d. The human alpha globin gene and the mouse alpha globin gene are orthologous to each other.arrow_forwardFrom the results of the experiment , explain how we know that the kiwis are more closely related to the emu and cassowary than to the moas. Cite particular regions in the sequences that support your answer.arrow_forwardEach of the following three questions contains two lists. The first is a list of some characteristics of our own species, Homo sapiens, that distinguish it from LUCA. The second is a list of possible sequences (reading from left to right) in which these novelties were acquired by our ancestors during the course of human evolution. Choose the number of the correct sequence. If none is correct, choose "None of the above." Here is the first pair of lists: A. Bilateral symmetry B. Bony skeleton C. Mitochondria D. Notochord E. Multicellularity O D, E, B, A, C O C, E, A, D, B O E, C, A, D, B O A, E, C, D, B O None of the abovearrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
- Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSONBiology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStaxAnatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
- Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & CompanyLaboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License