Statistics: The Art and Science of Learning from Data (4th Edition)
Statistics: The Art and Science of Learning from Data (4th Edition)
4th Edition
ISBN: 9780321997838
Author: Alan Agresti, Christine A. Franklin, Bernhard Klingenberg
Publisher: PEARSON
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Chapter 11, Problem 74CP
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The following are suggested designs for group sequential studies. Using PROCSEQDESIGN, provide the following for the design O’Brien Fleming and Pocock.• The critical boundary values for each analysis of the data• The expected sample sizes at each interim analysisAssume the standardized Z score method for calculating boundaries.Investigators are evaluating the success rate of a novel drug for treating a certain type ofbacterial wound infection. Since no existing treatment exists, they have planned a one-armstudy. They wish to test whether the success rate of the drug is better than 50%, whichthey have defined as the null success rate. Preliminary testing has estimated the successrate of the drug at 55%. The investigators are eager to get the drug into production andwould like to plan for 9 interim analyses (10 analyzes in total) of the data. Assume thesignificance level is 5% and power is 90%.Besides, draw a combined boundary plot (OBF, POC, and HP)
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Chapter 11 Solutions

Statistics: The Art and Science of Learning from Data (4th Edition)

Ch. 11.2 - Marital happiness and income In Exercise 11.5 when...Ch. 11.2 - First and second free throw independent? In pro...Ch. 11.2 - Cigarettes and marijuana The table on the...Ch. 11.2 - Prob. 14PBCh. 11.2 - Help the environment In 2010 the GSS asked whether...Ch. 11.2 - Prob. 16PBCh. 11.2 - Aspirin and heart attacks A Swedish study used...Ch. 11.2 - z test for heart attack study Refer to the...Ch. 11.2 - Severity of fever after flu shot The study...Ch. 11.2 - Prob. 20PBCh. 11.2 - Testing a genetic theory In an experiment on...Ch. 11.2 - Birthdays by quarters Based on a random sample of...Ch. 11.2 - Checking a roulette wheel Karl Pearson devised the...Ch. 11.3 - Democrat, race, and gender The two tables show...Ch. 11.3 - Death penalty associations Table 11.10, summarized...Ch. 11.3 - Smoking and alcohol The table refers to a survey...Ch. 11.3 - Sex of victim and offender For murders in the...Ch. 11.3 - Smelling and mortality A recent study (Pinto et...Ch. 11.3 - Vioxx In September 2004, the pharmaceutical...Ch. 11.3 - Egg and cell derived vaccine When comparing the...Ch. 11.3 - Risk of dying for teenagers According to...Ch. 11.3 - Marital happiness The table shows 2012 GSS data on...Ch. 11.3 - Party ID and gender The table shows the 2012 GSS...Ch. 11.3 - Chi-squared versus measuring association For the...Ch. 11.4 - Standardized residuals for happiness and income...Ch. 11.4 - Prob. 36PBCh. 11.4 - Prob. 37PBCh. 11.4 - Prob. 38PBCh. 11.4 - Prob. 39PBCh. 11.4 - Prob. 40PBCh. 11.5 - Keeping old dogs mentally sharp In an experiment...Ch. 11.5 - Prob. 43PBCh. 11.5 - Prob. 44PBCh. 11.5 - Prob. 46PBCh. 11 - Female for president? When recent General Social...Ch. 11 - Prob. 48CPCh. 11 - Down and chi-squared For the data in the previous...Ch. 11 - Prob. 50CPCh. 11 - Prob. 51CPCh. 11 - Prob. 52CPCh. 11 - Prob. 53CPCh. 11 - Prob. 54CPCh. 11 - Prob. 55CPCh. 11 - Prob. 56CPCh. 11 - Seat belt helps? The table refers to passengers in...Ch. 11 - Prob. 58CPCh. 11 - Prob. 59CPCh. 11 - Prob. 60CPCh. 11 - Prob. 61CPCh. 11 - Prob. 62CPCh. 11 - Prob. 63CPCh. 11 - Prob. 64CPCh. 11 - Clarity of diamonds Does the clarity of a diamond...Ch. 11 - Benfords Law When looking at a collection of...Ch. 11 - Prob. 67CPCh. 11 - Prob. 68CPCh. 11 - Prob. 70CPCh. 11 - Prob. 71CPCh. 11 - Prob. 72CPCh. 11 - Prob. 73CPCh. 11 - Prob. 74CPCh. 11 - Prob. 75CPCh. 11 - Prob. 76CPCh. 11 - Prob. 77CPCh. 11 - Prob. 78CPCh. 11 - Prob. 79CPCh. 11 - Statistical versus practical significance In any...Ch. 11 - Prob. 81CPCh. 11 - Multiple response variables Each subject in a...Ch. 11 - Standardized residuals for 2 2 tables The table...Ch. 11 - Prob. 84CPCh. 11 - Prob. 85CPCh. 11 - Prob. 86CPCh. 11 - Prob. 87CPCh. 11 - Prob. 88CPCh. 11 - Voting with 16 A recent survey of Austrian high...
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