Campbell Essential Biology (6th Edition) - standalone book
6th Edition
ISBN: 9780133917789
Author: Eric J. Simon, Jean L. Dickey, Jane B. Reece, Kelly A. Hogan
Publisher: PEARSON
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Textbook Question
Chapter 11, Problem 11SQ
What is the difference between oncogenes and proto-oncogenes? How can one turn into the other? What function do proto-oncogenes serve?
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What is a proto-oncogene? What are the typical functions of proteinsencoded by proto-oncogenes? At the level of protein function,what are the general ways that proto-oncogenes can beconverted to oncogenes?
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Chapter 11 Solutions
Campbell Essential Biology (6th Edition) - standalone book
Ch. 11 - Your bore cells, muscle cells, and skin cells look...Ch. 11 - A group of prokaryotic genes with related...Ch. 11 - The regulation of gene expression must be more...Ch. 11 - A eukaryotic gene was inserted into the DNA of a...Ch. 11 - How does DNA packing in chromosomes prevent gene...Ch. 11 - What evidence demonstrates that differentiated...Ch. 11 - The most common procedure for cloning an animal is...Ch. 11 - Prob. 8SQCh. 11 - Prob. 9SQCh. 11 - Prob. 10SQ
Ch. 11 - What is the difference between oncogenes and...Ch. 11 - Prob. 12SQCh. 11 - Prob. 13PSCh. 11 - The human body has a far greater variety of...Ch. 11 - Because a cat must have both orange and non-orange...Ch. 11 - Design a DNA microarray experiment that measures...Ch. 11 - Prob. 17PSCh. 11 - Prob. 18BSCh. 11 - Prob. 19BS
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- How can oncogenes lead to cancer?arrow_forwardProto-oncogenes can change into oncogenes that cause cancer.Which of the following best explains the presence of thesepotential time bombs in eukaryotic cells?(A) Proto-oncogenes first arose from viral infections.(B) Proto-oncogenes are mutant versions of normal genes.(C) Proto-oncogenes are genetic “junk.”(D) Proto-oncogenes normally help regulate cell division.arrow_forwardWhich of the following is an example of a proto-oncogene? 1) cell cycle inhibitor 2) tumor suppressor 3) oncogene 4) repair enzyme 5) growth factor receptorarrow_forward
- Suppose a gain-of-function mutation happens in an oncogene. Which of the following changes is likely to result? O a) tumor-promoting inflammation O b) evading growth suppressors Oc) sustaining proliferative signalling O d) resisting cell deatharrow_forwardWhat is the experimental evidence that demonstrates direct evidence that chemical carcinogens are able to produce oncogenes?arrow_forwardIdentify two genetic mechanisms whereby proto-oncogenes can become overexpressed. Select the two mechanisms. Identify two genetic mechanisms whereby proto-oncogenes can become overexpressed.Select the two mechanisms. 1) alterations in chromatin structure 2) a gain-of-function alteration 3)modification of proto-oncogenes products 4)mutations that result in an abnormal protein product 5)mutations within gene-regulatory regionsarrow_forward
- /20. In class, we discussed diffferent types of genetic change that can cause a normal gene (proto- oncogene) to become a cancer-causing gene (oncogene), Which of the following would not be a cause? A) translocation or transposition (movement of DNA within the same genome) B) gene ampliffication (increased number of copies of a given gene) C) epigenetic change D) point mutation that changes the gene's product E) loss of telomeres during DNA replication ancer?arrow_forwardWhy are proto-oncogenes present in non-cancerous cells? A one sentence answer is fine.arrow_forwardCan you please answer 16,17, and 18 pleasearrow_forward
- Can you please answer questions 13,14, and 15 pleasearrow_forwardWhat role does p53 signaling play in normal cells?arrow_forwardMany oncogenes result from mutations that cause excessive expression of a protein in cells where it is normally not expressed or is expressed at inappropriate times during development. This type of mutation can be described as ________. A) amorphic B) hypomorphic C)hypermorphic D) neomorphic E) dominant negativearrow_forward
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