Microbiology: A Systems Approach
Microbiology: A Systems Approach
4th Edition
ISBN: 9780073402437
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 10.4, Problem 9AYP
Summary Introduction

To describe:

The miRNAs and ways in which their discovery can impact human disease.

Concept introduction

Gene therapy is a method to treat the genetics related problems. In this therapy, nucleic acids are delivered to patients as a medicine or drug to treat the genes related problems. Gene therapy technique was modified by Martin Cline in 1980.

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The RNAi and the microRNA (miRNA) pathways share many components and characteristics. What unique feature distinguishes the microRNA pathway from RNAi? a) only the RNAi pathway is initiated by dsRNA molecules b) the miRNA pathway does not require Dicer c) the miRNA pathway does not require RISC. d) miRNAs have 100% complementarity with their mRNA targets to block translation e) siRNAs that act in RNAi have 100% complementarity with their mRNA targets resulting in endonucleolytic cleavage
The number of microRNAs encoded by the genome varies widely among organisms: some species have many miRNA genes and other species have relatively few. Researchers have determined the number of miRNA genes possessed by different species and have made the following observations: Q. The number of miRNA genes found on a chromosome is not correlated with chromosome length. In other words, longer chromosomes do not necessarily have more miRNA genes.
How is miRNA-206 beneficial to an organism?

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Microbiology: A Systems Approach

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QCE Biology: Introduction to Gene Expression; Author: Atomi;https://www.youtube.com/watch?v=a7hydUtCIJk;License: Standard YouTube License, CC-BY