Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 10, Problem 5P

In the following situations, what is the free energy change if 1 mole of Na + is transported across a membrane from a region where the concentrations is 1 μ m to a region where it is 100 mM? (Assume T=370C.)
a. In the absence of a membrane potential.
b. When the transport is opposed by a membrane potential of 70 mV.
c. In each case, will hydrolysis of 1 mole of ATP suffice to drive the transport of 1 mole of ion, assuming pH 7.4 and the following cytoplasmic concentrations: ATP =4.60 mM, Pi = 5.10 mM, ADP = 310 μ m?

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