Laboratory Manual Chemistry in Context
Laboratory Manual Chemistry in Context
8th Edition
ISBN: 9780073518121
Author: American Chemical Society
Publisher: McGraw-Hill Education
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Chapter 10, Problem 51Q
Interpretation Introduction

Interpretation:

In drug therapy treatment, how Habitrol and Bupropion differ in their approaches has to be given.

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Describe the principle of resonance and give a set of Lewis Structures to illustrate your explanation.
Don't used hand raiting
It is not unexpected that the methoxyl substituent on a cyclohexane ring prefers to adopt the equatorial conformation. OMe H A G₂ = +0.6 kcal/mol OMe What is unexpected is that the closely related 2-methoxytetrahydropyran prefers the axial conformation: H H OMe OMe A Gp=-0.6 kcal/mol Methoxy: CH3O group Please be specific and clearly write the reason why this is observed. This effect that provides stabilization of the axial OCH 3 group in this molecule is called the anomeric effect. [Recall in the way of example, the staggered conformer of ethane is more stable than eclipsed owing to bonding MO interacting with anti-bonding MO...]

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Laboratory Manual Chemistry in Context

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