Laboratory Manual Chemistry in Context
Laboratory Manual Chemistry in Context
8th Edition
ISBN: 9780073518121
Author: American Chemical Society
Publisher: McGraw-Hill Education
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Chapter 10, Problem 37Q
Interpretation Introduction

Interpretation:

Chiral carbon in L-DOPA has to be identified and the reason for why L-DOPA is effective against the muscular rigidity and the tremors related with Parkinson’s disease whereas D-DOPA is not has to be explained.

Concept Introduction:

Drugs: Drugs are molecules which are taken from an external source to change the normal functioning of the body. The action of drug is in molecular level and the design of many drugs are in such a way that it mimics a particular neurotransmitter or hormone. Drugs bind with receptors showing an increased or decreased effect.

Receptors: Receptors is a molecule or a part of molecule which interacts with a neurotransmitter, a hormone or other molecules which are biochemically active so that a response is initiated in a target cell.

Chirality: It refers to a Carbon atom in a molecule that contains four different substituents.

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These are synthesis questions. You need to show how the starting material can be converted into the product(s) shown. You may use any reactions we have learned. Show all the reagents you need. Show each molecule synthesized along the way and be sure to pay attention to the regiochemistry and stereochemistry preferences for each reaction. If a racemic molecule is made along the way, you need to draw both enantiomers and label the mixture as "racemic". All of the carbon atoms of the products must come from the starting material! ? H H
Q5: Draw every stereoisomer for 1-bromo-2-chloro-1,2-difluorocyclopentane. Clearly show stereochemistry by drawing the wedge-and-dashed bonds. Describe the relationship between each pair of the stereoisomers you have drawn.
Classify each pair of molecules according to whether or not they can participate in hydrogen bonding with one another. Participate in hydrogen bonding CH3COCH3 and CH3COCH2CH3 H2O and (CH3CH2)2CO CH3COCH3 and CH₂ CHO Answer Bank Do not participate in hydrogen bonding CH3CH2OH and HCHO CH3COCH2CH3 and CH3OH

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Laboratory Manual Chemistry in Context

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