Genetic Analysis: An Integrated Approach (3rd Edition)
Genetic Analysis: An Integrated Approach (3rd Edition)
3rd Edition
ISBN: 9780134605173
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 10, Problem 15P

A normal chromosome and its homolog carrying a paracentric inversion are given. The dot (•) represents the centromere.

Normal ABC •DEFGHIJK

Inversion abc •djihgfek

Diagram the alignment of chromosomes during prophase I.

Assume a crossover takes place in the region between F and G. Identify the gametes that are formedfollowing this crossover, and indicate which gametes are viable.

Assume a crossover takes place in the region between A and B. Identify the gametes that are formed by this crossover event, and indicate which gametes are viable.

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In Figure 17-28, what would be the consequence of acrossover between the centromere and locus A?
Changes in Chromosome Structure and Number An inversion heterozygote has homologous chromosomes with the following linkage arrangements:³ b • а b e a. What type of inversion is it? b. Draw the configuration of the chromosomes at synapsis of Prophase I. a с f d e d f с g c. If a four-strand double crossover occurs in the areas c-d (including chromatids 2 and 3) and e-f (including chromatids 1 and 4), what are the meiotic products? d. Repeat for a three-strand double crossover c-d (chromatids 2 and 3), and f-g (chromatids 1 and 3). e. For both types of double crossovers will any of the meiotic products be viable? If so which?
Inversions are known to affect crossing-over. The following homologs have the indicated order (the filled and open circles indicate centromeres): • (A B C D E) o (A D C B E)   b. Diagram the alignment of these chromosomes during meiosis.

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Genetic Analysis: An Integrated Approach (3rd Edition)

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