You have just created the world’s first genomic library from the African okapi, a relative of the giraffe. No genes from this genome have been previously isolated or described. You wish to isolate the gene encoding the oxygen-transporting protein b-globin from the okapi library. This gene has been isolated from humans, and its nucleotide sequence and amino acid sequence are available in databases. Using the information available about the human b-globin gene, what two strategies can you use to isolate this gene from the okapi library?

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Genome annotation

The technique of linking biological information to genome sequences is termed genome annotation. Gene annotation is the method of identifying gene locations and coding sections. It helps us understand what these genes are doing in the body through establishing structural characteristics and linking them to the actions of various proteins.