You are studying a novel viral protein. There is nothing known about the function of this protein. You analyze the protein sequence you observe an N- terminal sequence that looks like a signal sequence. To determine whether this sequence is in fact a signal sequence you clone the gene and make a mutation in the sequence, changing all of the amino acids in that region to alanine. You then look to see if the protein binds SRP and is brought to the ER. If your hypothesis is correct and it is in fact a signal sequence you should get the following results to your experiment. Select the outcome that supports your hypothesis. WT = wild-type, unmutated protein M= mutant, protein with signal sequence mutated to alanines O A. WT protein binds to SRP, localizes to ER M protein does not bind to SRP, is found in the cytosol O B. WT protein does not bind SRP, localizes to the ER M protein does not bind to SRP, is found in cytosol OC.WT protein does not bind to SRP, is found in the cytosol M protein binds to SRP, localizes to ER O D.WT protein binds to SRP, is found in the cytosol M protein binds to SRP, localizes to the ER

You are studying a novel viral protein. There is nothing known about the function of this protein. You analyze the protein sequence you observe an N- terminal sequence that looks like a signal sequence. To determine whether this sequence is in fact a signal sequence you clone the gene and make a mutation in the sequence, changing all of the amino acids in that region to alanine. You then look to see if the protein binds SRP and is brought to the ER. If your hypothesis is correct and it is in fact a signal sequence you should get the following results to your experiment. Select the outcome that supports your hypothesis. WT = wild-type, unmutated protein M= mutant, protein with signal sequence mutated to alanines O A. WT protein binds to SRP, localizes to ER M protein does not bind to SRP, is found in the cytosol O B. WT protein does not bind SRP, localizes to the ER M protein does not bind to SRP, is found in cytosol OC.WT protein does not bind to SRP, is found in the cytosol M protein binds to SRP, localizes to ER O D.WT protein binds to SRP, is found in the cytosol M protein binds to SRP, localizes to the ER

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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The new vaccines use messenger RNA (mRNA) in order to trigger the body into mounting an immune response against the viral particles of SARS-CoV-2. SARS-CoV-2 is the name of a type of coronavirus that causes the disease, Covid-19. As you know, mRNA carries the instructions to build proteins. What specific proteins does the mRNA in the adult Moderna vaccine code for?
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