Which of the following statements about how cells control the size of the poly-A tail on mRNA molecules in order to regulate translation initiation is FALSE? To inhibit translation initiation, a protein called CPEB binds to the CPE sequence on the mRNA. This will then bring in an enzyme called PARN. O If a kinase inhibitor was introduced, then Maskin and PARN would be able to continue to exert their inhibitory effect on translation initiation. To initiate translation, the protein CPEB gets phosphorylated by a specific kinase. This causes a conformational change that excludes both Maskin and PARN. O If a kinase inhibitor was introduced, then CPEB would be phosphorylated, so no conformational change would occur. Without Maskin and PARN, the poly-A tail can extend and eIF4E and eIF4G can interact with each other to initiate translation.

Which of the following statements about how cells control the size of the poly-A tail on mRNA molecules in order to regulate translation initiation is FALSE? To inhibit translation initiation, a protein called CPEB binds to the CPE sequence on the mRNA. This will then bring in an enzyme called PARN. O If a kinase inhibitor was introduced, then Maskin and PARN would be able to continue to exert their inhibitory effect on translation initiation. To initiate translation, the protein CPEB gets phosphorylated by a specific kinase. This causes a conformational change that excludes both Maskin and PARN. O If a kinase inhibitor was introduced, then CPEB would be phosphorylated, so no conformational change would occur. Without Maskin and PARN, the poly-A tail can extend and eIF4E and eIF4G can interact with each other to initiate translation.

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter4: Cell Structure

Section: Chapter Questions

Problem 32CTQ: You already know that ribosomes are abundant in red blood cells. In what other cells of the body...

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