After the entire coding sequence of a protein has been decoded and the peptide chain is synthesized, it needs to be released from the final tRNA in the P site of the ribosome so it can float away from the ribosome to do its thing. Which of the following allows release of the peptide?- **[ ]** If no new aa-tRNAs can bind the codon near the A site, then eventually the peptidyltransferase site in the ribosome will function in reverse and cleave the bond between the peptide chain and the tRNA.- **[X]** A protein release factor enters the A site and base pairs with the stop codon when it is near the A site—this protein positions a water molecule and helps promote a hydrolysis reaction that releases the peptide chain from the tRNA.- **[ ]** A leprechaun is attracted to the stop codon when it is near A site, and it pours Guinness on the bond between the peptide and the tRNA, which cleaves the covalent bond.- **[ ]** The 30S and 50S subunits disassociate as soon as the stop codon enters the 30S subunit—then the peptide-tRNA float out of the 50S subunit and are cleaved by an amino-acyl transferase. **Question:**Which of the following events would NOT result in ribosomes stalling on an mRNA during translation?**Options:**1. The mRNA in a given region is very highly folded, and the ribosome stalls because the mRNA structure blocks its movement.2. The correct tRNA is scarce because it is not transcribed very much in the prevailing conditions. The ribosome stalls while waiting for one of the scarce tRNAs to diffuse into the A site.3. The release factor enters the A site, decodes a stop codon and transfers an oxygen from water to the carboxyl group of the peptidyl-tRNA in the P site, causing stalling.4. Starvation for amino acids will reduce the amount of amino-acylated (charged) tRNA. The ribosome will stall while waiting for a charged tRNA to enter the A site to decode the next codon.

Translation is a process of protein synthesis. It is completed in three steps- Initiation…

After the entire coding sequence of a protein has been decoded and the peptide chain is synthesized, it needs to be released from the final tRNA in the P site of the ribosome so it can float away from the ribosome to do its thing. Which of the following allows release of the peptide? If no new aa-tRNAS can bind the codon near the A site, then eventually the peptidyltransferase site in the ribosome will function in reverse and cleave the bond between the peptide chain and the TRNA O A protein release factor enters the A site and base pairs with the stop codon when it is near the A site - this protein positions a water molecule and helps promote a hydrolysis reaction that releases the peptide chain from the tRNA O A leprechaun is attracted to the stop codon when it is near A site, and it pours Guinness on the bond between the peptide and the tRNA, which cleaves the bond O The 305 and 505 subunits disassociate as soon at the stop codon enters the 305 subunit- then the peptide-tRNA float out of the 505 subunit and are cleaved by an amino-acyl transferase

After the entire coding sequence of a protein has been decoded and the peptide chain is synthesized, it needs to be released from the final tRNA in the P site of the ribosome so it can float away from the ribosome to do its thing. Which of the following allows release of the peptide? If no new aa-tRNAS can bind the codon near the A site, then eventually the peptidyltransferase site in the ribosome will function in reverse and cleave the bond between the peptide chain and the TRNA O A protein release factor enters the A site and base pairs with the stop codon when it is near the A site - this protein positions a water molecule and helps promote a hydrolysis reaction that releases the peptide chain from the tRNA O A leprechaun is attracted to the stop codon when it is near A site, and it pours Guinness on the bond between the peptide and the tRNA, which cleaves the bond O The 305 and 505 subunits disassociate as soon at the stop codon enters the 305 subunit- then the peptide-tRNA float out of the 505 subunit and are cleaved by an amino-acyl transferase

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Which of the following is the initiator tRNA for all bacterial proteins? Formyl-cysteinyl-TRNA(ACG) Formyl-methionyl-TRNA(UAC) Tryptophanyl- RNA(CGU) Valyl-TRNA (CAG)
Order the following choices to indicate the sequence of steps in the process of elongation of agrowing peptide chain. a. release of EF1-GDPb. EF2-GTP hydrolysis promotes translocation of the ribosomec. peptidyltransferase reaction catalyzed by large rRNA subunitd. aminoacyl-tRNA binds the ribosomal A site via EF1-GTP hydrolysis
Using the given information, determine the correct order of the following events during translation: TRNA-methionine is cleaved and moves the empty tRNA to E site & is released, TRNA with polypeptide chain moves to P site. Second tRNA binds to 1. Step 1 codon in A site 2. Step 2 Ribosome arrives at stop codon & polypeptide chain is released from TRNA 3. Step 3 4. Step 4 A peptide bond is created between the first amino acid and the second amino 5. Step 5 acid. 6. Step 6 TRNA-methionine binds to the start codon and the large ribosomal unit binds Small subunit scans MRNA until it reaches start codon
Vaccina virus (used in the polio vaccine) produces an enzyme that takes the 5’ cap off of the mRNAs in the eukaryotic cells it infects. Besides allowing degradation of the host’s mRNA, what step in translation of the host’s mRNAs does this prevent? Group of answer choices Movement of tRNA from the A site to the P site tRNA binding to the A site Recognition of the stop codon Ribosome small subunit from binding mRNA Movement of the tRNA from the P site to the A site
The synthesis of a protein requires that the amino acids that constitute the growing polypeptide chain be covalently linked to the amino acid attached to the tRNA at the aminoacyl site of the ribosome. Which of the following catalyses this reaction? Options: the aminoacyl tRNA synthetase eEF2 eEF1-GTP a large ribosomal RNA the initiator tRNA met
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The figure below shows a ribosome in the process of translating an mRNA with a sequence: 5'...AUGCCGUAUGCUCUUUAA..3' a) The right side shows the ribosome with an empty A site aligned with the codon 5'UAU3'. The next tRNA to occupy the A site on the ribosome will have what anti-codon sequence (label 5' and 3')? Keep in mind the wobble pairing rules and make sure your answer is consistent with the genetic code. Explain your answer. b) Suppose, just as the ribosome started translating the mRNA, the cell suddenly lost all of its alanine tRNAs. Using the figure as a guide, draw and label the state the ribosome would arrest in.
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