Which of the following is most likely to cause accumulation of acetyl CoA? Group of answer choices There is not enough oxaloacetate present to run the citric acid cycle Increase activity of pyruvate dehydrogenase kinase Increased fatty acid synthesis Increased citrate synthase activity   When fluoroacetate (an analog of acetate) is added to the mitochondria, it causes build up of fluorocitrate. Which of the following is most likely to be true? Group of answer choices Fluoroacetate cannot be converted to fluoroacetyl CoA Fluoroacetyl CoA cannot be combined with oxaloacetate to enter the citric acid cycle Addition of fluoroacetate will cause an increase in isocitrate Aconitase cannot use fluorocitrate as a substrate

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Which of the following is most likely to cause accumulation of acetyl CoA?

Group of answer choices
There is not enough oxaloacetate present to run the citric acid cycle
Increase activity of pyruvate dehydrogenase kinase
Increased fatty acid synthesis
Increased citrate synthase activity
 

When fluoroacetate (an analog of acetate) is added to the mitochondria, it causes build up of fluorocitrate. Which of the following is most likely to be true?

Group of answer choices
Fluoroacetate cannot be converted to fluoroacetyl CoA

Fluoroacetyl CoA cannot be combined with oxaloacetate to enter the citric acid cycle

Addition of fluoroacetate will cause an increase in isocitrate
Aconitase cannot use fluorocitrate as a substrate
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