The acetyl group shuttle transfers the acetyl group of acetyl-CoA, produced by oxidative decarboxylation of pyruvate in themitochondrion, to the cytosol.What is the overall equation for the transfer of one acetyl group from the mitochondrion to the cytosol?Acetyl-CoA,(mit)+What is the cost of thicost of shuttling an adATP + CoA (cyt)CoA (cyt) +NADH + H+2 ATPNAD+ +ATPcitrate + ATP→acetyl-CoA (cyt) +roup?NADH + H+ +ADP +P;ADP + P + CoA (mit)CoA (mit)oxaloacetate + ADP + P₁2 ADP + 2 P₁+ NAD+ATP(s) What is the cost of this process in ATPs per acetyl group?cost of shuttling an acetyl group:ATP(s)The acyl group shuttle transfers fatty acyl-CoA from the cytosol to the mitochondrion in preparation for ß oxidation, separatingthe mitochondrial and cytosolic pools of CoA.Does the acetyl group shuttle also keep mitochondrial and cytosolic pools of CoA separate?Yes, because the shuttle requires the release of one mitochondrial CoA and the input of one cytosolic CoA.Yes, because CoA formed in the mitochondrion remains in the mitochondrion, whereas CoA formed in the cytosolremains in the cytosol.No, because CoA can diffuse across the inner mitochondrial membrane.No, because there is no cytosolic pool of CoA because CoA is formed in the mitochondrion.

Acetyl CoA is produced in mitochondria and cannot leave mitochondria so it combines with…

Answered: The acetyl group shuttle transfers the…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Similar questions

If decanoic acid (10 : 0) undergoes complete β-oxidation in mitochondria, how many net ATP is yielded? (NADH = 2.5 ATP; FADH2 = 1.5 ATP; Acetyl CoA = 10 ATP) Answer in number only
If 30 molecules of acetyl CoA enter into the mitochondria in the presence of O2, how many molecules of ATP will be formed through oxidative phosphorylation?
Medical researchers are studying a patient with the newly discovered u LEKS metabolic syndrome, in which a genetic mutaton prevents NADH produced in the cytosol from being reoxidized by the electron transport chain. Suppose the following nutrient molecule is digested and metabolized by this patient under anaerobic conditions, e.g. during a sudden intense exertion: de HO-CH: -OH Он н. HO H OH How many ATP molecules will uttimately be produced by the catabolism of this molecule? Note: you can ussume the catabohism is as complete as it can be under the conditions given above. How many molecules of pyruvate will be produced during dycalysist How many maleoules of lactate will be produced
if each NADH generates 3 ATP molecules and each FADH2 generates 2 ATP molecules, calculate the number of ATP molecules generated from one saturated 10-carbon fatty acid Determine the number of repetitions of the β‑oxidation spiral needed to completely degrade the fatty acid to acetyl-SCoAacetyl-SCoA (acetyl-CoA)(acetyl-CoA) . Calculate the ATPATP produced by the acetyl-SCoAacetyl-SCoA molecules in the citric acid cycle. Calculate the ATPATP produced from the FADH2FADH2 and NADHNADH produced from β‑oxidation. Add the ATPATP generated (from step 2 and 3), and subtract the ATPATP needed to activate the fatty acid.
Describe the mechanism for moving acetyl-CoA produced in the mitochondrial matrix into the cytosol for fatty acid synthesis.
We have described an ATP synthase complex with an Fo complex of 9 c-subunits. Consider if the F0 complex had 12 c- subunits instead of only 9 (assume a eukaryote). What would be the P/O ratio (the ATP produced in the cytosol per atom of O reduced (or a pair of e- if you want to think of it that way) obtained from using B-hydroxy-fatty-acyl-CoA Dehydrogenase? (report to 1 decimal place) ATP
The following two reactions are coupled in the last step of glycolysis (catalyzed by the enzyme pyruvate kinase). РЕР + Н.О € Руr + Pi ADP + Pi → ATP + H2O AG° = -14.8 kcal/mol AG° = +7.3 kcal/mol D) The steady-state concentrations of ATP, ADP, and pyruvate in human erythrocytes are 2.24 mM, 0.25 mM, and 0.051 mM, respectively. What would be the concentration of PEP in these cells if the coupled reaction was at equilibrium?
Write the equation for net citric acid cycle and calculate one cycle equivalent to how many ATP?
The mitochondrial Pyruvate Dehydrogenase Complex (PDC) is a very large enzyme complex which catalyses the oxidative decarboxylation of pyruvate to acetyl-CoA. Describe the enzyme components that make up the PDC, indicating the contribution each makes to the pyruvate to acetyl-CoA process, as well as how the PDC itself is regulated by intermediates?
in the mitochondria pyruvate is converted into acetyl CoA so then acetyl CoA make its way to the TCA cycle and produces energy sources for oxidative phosphorylation. Pyruvate oxidation transforms pyruvate, a three-carbon molecule, into acetyl, a two-carbon molecule linked to Coenzyme A, generating NADH and releasing one carbon dioxide molecule in process the citric acid cycle is fundamental because runs on acetyl CoA as its fuel. i need more explanantion
What one carbon waste product of cellular respiration is formed as the 3 carbon product of glycolysis enters the mitochondria and becomes a 2 carbon Acetyl CoA?
In the first step of the TCA cycle the acetyl group of acetyl-CoA is transferred to oxaloacetate to produce citrate. Where will the carbonyl carbon of that acetyl group be after the first CO2 is expelled? Group of answer choices The first carbon of α-ketoglutarate The last carbon of α-ketoglutarate The fourth carbon of α-ketoglutarate The third carbon of α-ketoglutarate

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