A new weight loss drug, Super Fat Melter, is introduced on the market but then quickly recalled after a few patients die. As it turns out, the pill makes the lipid bilayer of the inner mitochondrial membrane leaky to H+. What impact does this have on ATP production? Explain, with reference to the type of phosphorylation affected.

Q: How do you think ATP is made accessible to enzymes in the cytosol and other organelles?

A: Mitochondria are an important organelles  which is also known as powerhouse of the cell that do…

Q: Given the overall equation for respiration (C6H12O6 + 6O2 6CO2 + 6H2O), in which step(s) in the…

A: Respiration is the process by which organisms convert organic matter, such as glucose, into energy…

Q: Glucose is phosphorylated to glucose-6-phosphate by hexokinase in the first step of the glycolytic…

A: Reactions that have a positive value of Delta G are not favorable in nature. Hence in order to…

Q: How many ATPs would result from the reaction involving the alpha-ketoacid dehydrogenase complex…

A: 1 mole of a substance consists of 6.02 x 1023 molecules.1 mole of glucose would consist of 6.02 x…

Q: (A) What is the free energy yield associated with the transport of a proton from the mitochondrial…

A: Given,△G = RTlnKeq. Also given that pH of IMS is 1.4 units lower than pH of the matrix. R =…

Q: The maintenance of a proton motive force across the inner mitochondrial membrane is crucial for…

A: Uncoupling protein is a Proton channel located on the inner mitochondrial membrane. It dissipates…

Q: How many ATP are produced from the complete degradation of G3P using glycerol- three phosphate…

A: The glycerol-3-phosphate shuttle is a mechanism that regenerates NAD+ from NADH that is a by-product…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.