A fatty acid (a long straight-chain carboxylic acid with an even number of carbons) is metabolized to acetyl- CoA, which can then enter the citric acid cycle to be further metabolized (Section 24.9). A fatty acid with anodd number of carbons is metabolized to acetyl-CoA and one equivalent of propionyl-CoA. Propionyl-CoA cannot enter the citric acid cycle. Two coenzyme-requiring enzymes are needed to convert it to succinyl-CoA, acompound that can enter the citric acid cycle. Write the two enzyme-catalyzed reactions and include the names of the required coenzymes.

Q: In the human body, under oxygen rich and oxygen poor conditions, respectively, pyruvate is converted…

A: Pyruvate has different fates under oxygen-rich and oxygen-poor conditions.

Q: If Vitamin B1 is deficient, which of the following intermediates is/are likely to accumulate…

A: Vitamin B1, also known as thiamine, is an essential water-soluble vitamin that plays a critical role…

Q: The CO2 produced in one round of the citric acid cycle does not originate in the acetyl carbons that…

A: Cellular Respiration is the oxidative process through which energy is obtained from the food. The…

Q: Deficiencies in the conversion of Pyruvate to Acetyl CoA may result in severe neurological…

A: Conversion of pyruvate to acetyl-CoA is the reaction that links glycolysis with the TCA…

Q: After the formation of pyruvic acid it must be converted into Acetyl CoA to enter the Krebs cycle…

A: Cellular respiration involves  breakdown of glucose through a series of catabolic steps in the cell…

Q: True or false Ketone body synthesis requires transportation of acetyl-CoA through the inner…

A: Acetone, acetoacetate and 3 beta hydroxybutyrate are known as ketone bodies. They are produced from…

Q: After several days of starvation, the capacity of the liver to metabolize acetyl-CoA via the citric…

A: The citric acid cycle is involved in cell respiration and produces NADH and FADH2 for the electron…

Q: Do you think that the reverse of the reaction given, (Malonyl-CoA → Acetyl-CoA + HCO3-) must be…

A: Detailed explanation: Yes, the reverse reaction of Malonyl-CoA converting to Acetyl-CoA and HCO3-…

Q: Stearic acid is the common name for the C18 straight-chain, saturated fatty acid. Draw the structure…

A: A long aliphatic chain of saturated or unsaturated attached to a carboxylic acid is called Fatty…

Q: Saturated fatty acids are degraded by the stepwise reactions of oxidation, producing acetyl-CoA.…

A: Simple fats or triglycerides or triacylglycerides are categorized as storage lipids. Triglycerides…

Q: why is much of acetyl-CoA resulting from ethanol metabolism is used in fatty acid synthesis rather…

A: CH3-CH2-OH --------> CH3-COO-  Acetyl co A is produced from ethanol by alcohol dehydrogenase by…

Q: acetyl CoA

A: Acetyl CoA is a central metabolite that plays important roles in energy production as well as…

Q: The CO2 produced in one round of the citric acid cycle does not originate in the acetyl carbons that…

A: Cellular respiration is a series of chemical reactions that cells use to break down glucose and…

Q: How does oxaloacetate get to the cytoplasm (from mitochondria matrix) for gluconeogenesis?…

A: Gluconeogenesis is the process of the synthesis of glucose from non-carbohydrate sources. where…

Q: A fatty acid (a long straight-chain carboxylic acid with an even number of carbons) is metabolized…

A: The β-oxidation pathway completes the degradation of saturated fatty acids having an even number of…

Q: Enzyme involved in the synthesis of the compound forming bile salts and stero hormones Acetyl CoA…

A: The 7α-hydroxylase cholesterol (CYP 7A1) is the key enzyme in the catabolic pathway that determines…

Q: How similar of an effect would a mutation in pyruvate dehydrogenase have, compared to a mutation in…

A: In glycolysis, a 6-carbon molecule of glucose-6-phosphate is broken down into 3-carbon pyruvate by…

Q: Which of the following statements is TRUE about fatty acid biosynthesis? Citrate carries malonyl CoA…

A: Triacylglycerol are the triesters of glycerol and fatty acids. Each molecule of glycerol is bonded…

Q: Draw the steps involved in the catabolism of thymine into malonyl-CoA. Include the names and…

A: Nucleic acids are composed of nucleotides, and nucleotides are composed of a pentose sugar,…

Metabolic pathways

Metabolism is defined as the group of life-supporting, enzyme-mediated chemical reactions in organisms. A metabolic pathway is a set of these chemical reactions that involve anabolism (synthesis of complex biomolecules) and catabolism (breakdown of biomolecules into small molecules) that occur inside a cell. Metabolites are the reacting substances, products, and intermediate substances of an enzymatic process that are altered by a series of chemical events catalyzed by enzymes.