There is a protein called neurogenin that stimulates neuronal cells to differentiate. In order to determine what kind of receptor neurogenin binds to, you add a general phosphatase (one that can remove phosphates from any substrate) to neural cells when you add neurogenin, and you discover that this inhibits differentiation. Furthermore, in the presence of this phosphatase, you find that not even a G protein is activated in response to neurogenin. 1. With this information, what kind of receptor does neurogenin bind to?

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There is a protein called neurogenin that stimulates neuronal cells to differentiate. In order to determine what kind of receptor neurogenin binds to, you add a general phosphatase (one that can remove phosphates from any substrate) to neural cells when you add neurogenin, and you discover that this inhibits differentiation. Furthermore, in the presence of this phosphatase, you find that not even a G protein is activated in response to neurogenin.

1.  With this information, what kind of receptor does neurogenin bind to?

2.  In a normal cell, how does the G protein in this pathway get activated?

3.  In a normal cell, why does the response to neurogenin cease over time?

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