The steady-state kinetics of an enzyme has been studied in the absence and presence of an inhibitor (Inhibitor A). The initial rate given as a function of substrate concentration in the following table: Substrate Concentration, [S] Initial rate, v, (mmol/L-min) Initial rate, v, (mmol/L-min) (mmol/L) No Inhibitor With Inhibitor A 1.25 1.72 0.98 1.67 2.04 1.17 2.50 2.63 1.47 5.00 3.33 1.96 10.00 4.17 2.38
The steady-state kinetics of an enzyme has been studied in the absence and presence of an inhibitor (Inhibitor A). The initial rate given as a function of substrate concentration in the following table: Substrate Concentration, [S] Initial rate, v, (mmol/L-min) Initial rate, v, (mmol/L-min) (mmol/L) No Inhibitor With Inhibitor A 1.25 1.72 0.98 1.67 2.04 1.17 2.50 2.63 1.47 5.00 3.33 1.96 10.00 4.17 2.38
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
Related questions
Question
1. As seen in the picture:
- What kind of inhibition (competitive, uncompetitive, mixed) is involved?
- Calculate Vmax and Kmax in the absence and presence of inhibitor A
Show complete solution.
![The steady-state kinetics of an enzyme has been studied in the absence and presence of an inhibitor (Inhibitor A). The initial rate
given as a function of substrate concentration in the following table:
Substrate Concentration, [S]
Initial rate, v, (mmol/L-min)
No Inhibitor
1.72
Initial rate, v, (mmol/L-min)
With Inhibitor A
(mmol/L)
1.25
0.98
1.67
2.04
1.17
2.50
2.63
1.47
5.00
3.33
1.96
10.00
4.17
2.38](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fd8dc393c-f7c4-495f-aaeb-919425d33078%2Fd1a86ada-4820-42ff-a4d6-e0aff1c42c7e%2Fc65md27_processed.jpeg&w=3840&q=75)
Transcribed Image Text:The steady-state kinetics of an enzyme has been studied in the absence and presence of an inhibitor (Inhibitor A). The initial rate
given as a function of substrate concentration in the following table:
Substrate Concentration, [S]
Initial rate, v, (mmol/L-min)
No Inhibitor
1.72
Initial rate, v, (mmol/L-min)
With Inhibitor A
(mmol/L)
1.25
0.98
1.67
2.04
1.17
2.50
2.63
1.47
5.00
3.33
1.96
10.00
4.17
2.38
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