The previous scenario is a greatly-simplified demonstration of how antibiotic resistance is selected for in bacteria. It assumes bacterial cells are either totally resistant (BR+, red cells) or completely susceptible (BRo, yellow). In reality, just like people differ in height, with many different heights possible, bacteria in a population can differ along a whole spectrum of resistance. Drag and Drop these labels on to the graph. One label will not be used Least Resistant Use of brincomycin selects FOR Use of brincomycin selects AGAINST these cells these cells Spectrum of Resistance Number of cells Most Resistant
Bacterial Genomics
The study of the morphological, physiological, and evolutionary aspects of the bacterial genome is referred to as bacterial genomics. This subdisciplinary field aids in understanding how genes are assembled into genomes. Further, bacterial or microbial genomics has helped researchers in understanding the pathogenicity of bacteria and other microbes.
Transformation Experiment in Bacteria
In the discovery of genetic material, the experiment conducted by Frederick Griffith on Streptococcus pneumonia proved to be a stepping stone.
Plasmids and Vectors
The DNA molecule that exists in a circular shape and is smaller in size which is capable of its replication is called Plasmids. In other words, it is called extra-chromosomal plasmid DNA. Vectors are the molecule which is capable of carrying genetic material which can be transferred into another cell and further carry out replication and expression. Plasmids can act as vectors.
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Drawing
The previous scenario is a greatly-simplified demonstration of how antibiotic resistance is selected for in bacteria.
It assumes bacterial cells are either totally resistant (BR+, red cells) or completely susceptible (BRo, yellow). In
reality, just like people differ in height, with many different heights possible, bacteria in a population can differ
along a whole spectrum of resistance.
Drag and Drop these labels on to the graph. One
label will not be used
Least Resistant
Use of
Use of
brincomycin
selects AGAINST
brincomycin
selects FOR
these cells
these cells
Spectrum of
Resistance
Number of cells
Most Resistant
Notes
Comments
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