A gut epithelial cell line that has been genetically engineered to express acommon cystic-fibrosis-causing CFTR mutation is accidentally cross-contaminated with cholera bacteria from another experiment. Given whatyou know of CFTR's role in both disease states, what is a likely outcome?Cl- rushes out of the cells.O CI- rushes into the cells.O CI- levels are unchanged but Na+ is driven out of the cells.CI- levels in the cells are unaffected.

Cholera is a bacterial disease characterized by diarrhoea and dehydration. The disease is caused by…

Answered: A gut epithelial cell line that has…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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VEGF is synthetized in cancer cell to promote angiogenesis. Which sentence is correct? Polypeptide chain is synthesized on ribosomes attached to the ER (rough ER), and translocated through the membrane to the lumen by protein translocator, which is constantly active; mature VEGF chain is released to the lumen through signal peptidase cleavage. Polypeptide chain is synthesized on ribosomes attached to the ER (rough ER), and translocated through the membrane to the lumen by protein translocator, which is activated by start-transfer sequence; mature VEGF chain is . Polypeptide chain is synthesized on ribosomes attached to the ER (rough ER), and translocated through the membrane to the lumen by protein translocator, which is activated by start-transfer sequence; mature VEGF chain remains embedded to the membrane for further transport Polypeptide chain is synthesized on ribosomes attached to the ER (rough ER), and translocated through the membrane to the lumen by protein translocator,…
Cystic fibrosis (CF) is a genetic disorder caused by mutations in the CFTR (cystic fibrosis transmembrane-conductance regulator) gene, which encodes the CFTR protein. The cells of the lining of the lungs contain high levels of the CFTR protein in their membranes. Normally, CFTR contains a chloride ion channel, which permits chloride ions to pass from inside the cells to the cells’ surfaces. The surface chloride ions are able to attract water in the lungs, allowing for the formation of a water layer on the cells’ surfaces. This thin water layer is necessary to allow the cilia, the tiny hairs on the surface of the lining cells to move back and forth easily. This motion permits the removal of mucus from the lungs. A particular error in the CFTR gene results in the replacement of the amino acid Phe with Ser at residue 508 of the CFTR protein. Individuals afflicted with CF most often experience the presence of thick, dry and sticky mucus in the lungs, leading to chronic infections and…
MACS are donut-shaped protein complexes of the complement system that create holes in bacterial cells to cause apoptosis. O 1) True O 2) False
can you explain why Bacillus anthracis can be pathogenic in a mouse and not be fought off by the immune system? I need help finding the answer in the article and explain in short answer link to article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC106848/
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In 2014, eleven Ebola virus infected patients were hospitalized in the United States. Some of these Ebola infected patients were treated with blood serum obtained from patients that had survived the Ebola virus infection . What was the rationale for using this serum? This blood serum contains anti-Ebola virus antibodies produced by the Ebola virus infection survivors. These antibodies may help the patient fight the Ebola infection. The blood serum of an individual that survived the Ebola virus infection contains B cells and T cells, which may help the patient fight the Ebola infection. This serum acts as a vaccine against Ebola because the Ebola virus infection survivors carry attenuated Ebola viruses. This serum is rich in natural killer cells, which may help the patient fight the Ebola infection.
A pathogenesis function f(t)t(t-21)(t + 1) is used to model the development of the disease, where t is measured in days and f(t) represents the number of infected cells per mL of plasma. What is the peak infection time for this virus? (Round your answer to one decimal place.) t= Need Help? X days Read It
The S (spike) glycoprotein of coronaviruses can engage receptors by the N-terminal domain, the C-terminal domain, or both. The C-terminal domains of both human SARS coronaviruses bind ACE2 (angiotensin-converting enzyme 2), whereas that of MERS-CoV binds DDP4 (dipeptidyl peptidase 4). In contrast, in mouse hepatitis coronavirus (MHV) the N-terminal domain of S binds CEACAM (cell adhesion molecule 1). You have identified a novel coronavirus with an S protein that displays similarity to MHV at the N terminus and to SARS at the C terminus. What are the molecules most likely to function as receptors and how will you test this?
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