Back to Mr. Doe and his MRSA which over time is becoming more and more resistant to brincomycin. In the diagram below time is moving from left to right. Drag-drop the arrow-labels and the captions to describe how Mr. Doe's MRSA is evolving resistance to brincomycin. You only need to label one moment of diffusion, one pump and one molecule of brincomycin. Time 1 Time 2 Time 3 Efflux Pump brincomycin Diffusion into cell MRSA MRSA MRSA Efflux pump removes MRSA Efflux pump grabs brincomycin as fast as it diffuses in, cell MRSA antibiotic better, pumps it out faster, less brincomycin stays in cell MRSA Efflux pump grabs antibiotic inefficiently, pumps it out slowly, brincomycin stays in cell long enough to not damaged by the antibiotic What is happening: damage it MIC = 8 MIC MIC =1 MIC =2

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Back to Mr. Doe and his MRSA which over time is becoming more and more resistant to brincomycin. In the
diagram below time is moving from left to right. Drag-drop the arrow-labels and the captions to describe how
Mr. Doe's MRSA is evolving resistance to brincomycin. You only need to label one moment of diffusion, one
pump and one molecule of brincomycin.
Time 1
Time 2
Time 3
brincomycin
Efflux Pump
Diffusion into cell
MRSA
MRSA
MRSA
Efflux pump removes
MRSA
Efflux pump grabs
brincomycin as fast
as it diffuses in, cell
MRSA
antibiotic better,
pumps it out faster,
less brincomycin
stays in cell
MRSA
Efflux pump grabs
antibiotic
inefficiently, pumps
it out slowly,
not damaged by the
antibiotic
What is happening:
brincomycin stays in
cell long enough to
damage it
MIC = 8
MIC
MIC = 1
MIC =2
E Notes
Comments
W
33°F
Transcribed Image Text:Back to Mr. Doe and his MRSA which over time is becoming more and more resistant to brincomycin. In the diagram below time is moving from left to right. Drag-drop the arrow-labels and the captions to describe how Mr. Doe's MRSA is evolving resistance to brincomycin. You only need to label one moment of diffusion, one pump and one molecule of brincomycin. Time 1 Time 2 Time 3 brincomycin Efflux Pump Diffusion into cell MRSA MRSA MRSA Efflux pump removes MRSA Efflux pump grabs brincomycin as fast as it diffuses in, cell MRSA antibiotic better, pumps it out faster, less brincomycin stays in cell MRSA Efflux pump grabs antibiotic inefficiently, pumps it out slowly, not damaged by the antibiotic What is happening: brincomycin stays in cell long enough to damage it MIC = 8 MIC MIC = 1 MIC =2 E Notes Comments W 33°F
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