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Curren'S Math For Meds: Dosages & Sol

Curren'S Math For Meds: Dosages & Sol

11th Edition

ISBN:9781305143531

Author:CURREN

Publisher:CURREN

Chapter10: Reconstitution Of Powdered Drugs

Section: Chapter Questions

Problem 4.2P

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Question

Target:
Antibiotic: Tetracyclive (TE)
Antibiotic: _Ciprofloxacin (Cip) Target:
Antibiotic: Penicillin (P)
Target:
Antibiotic: Trimethoprim sulfa Target:
Antibiotic: Polymyxin B (PB) Target:
Antibiotic: Steptomycin
(5) Target:

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For each of the following antibiotics, give the spectrum, primary effect and briefly explain the mechanism of action: 1) Penicillins 2) Po1yrrryxin B 3) Vancomycin 4) Tetracyclins
Antibiotics Neomycin Gentamicin Vancomycin Ampicillin Bacitracin Erythromycin Penicillin G Streptomycin Chloramphenicol Disc content 30 mcg 10 mcg 30 mcg 10 mcg 10 units 15 mcg 10 units 10 mcg 30 mcg Diameter of zone of inhibition (mm) Resistant (mm Intermediate or less) 12 12 14 13 8 13 11 12 (mm) 13-16 13-14 15-16 14-16 9-12 14-22 12-14 13-17 Sensitive (mm or more) 17 15 17 17 13 23 15 15 18 library Ⓒ Hudzicki CENTIMETERS LINCHES 22. Given the data (above) what can you conclude about using chloramphenicol to treat an infection caused by this microbe? A. the microbe is resistant B. this drug should be used only if there are no better options C. the microbe is sensitive to the drug D. cannot use this drug E. any zone of inhibition shows that a drug will be an effective treatment
Semi-synthetic and extended-spectrum penicillins have proven more effective than natural penicillins for two of the following reasons: 1-Interfere more effectively with the development of the peptidoglycan layer in cell-walls 2-Are less sensitive to penicillinases than natural penicillins 3-Do not contain the b-lactam ring thus making them less susceptible to b-lactamases 4-Are less susceptible to the development of resistance 5-Have a broader spectrum of activity
1) Match the antibiotics with their mechanism of action: mechnism of action: 1) nucleic acid synthesis inhibitor 2) Cell wall synthesis inhibitor 3) cell membrane disruptor 4) protein synthesis inhibitor 5) folic acid synthesis inhibitor
Describe five modes of action for antibiotics. For each, provide one example.
Answer all of the questions 1. Which of the following antimicrobial drugs target DNA/RNA synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 2. Which of the following antimicrobial drugs target protein synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 3. true or false: Streptococcus is killed by growing on blood agar.
Describe the difference between broad spectrum and narrow spectrum antibiotics. Describe the pros and cons of both types. Give specific examples of each type of antibiotic and tell what it’s mode of action is.
This petri plate shows the susceptibility of Staphylococcus aureus to different antibiotics. Which antibiotic is least effective? a) Methicillin - Meth b) Control c) All are ineffective d) Ampicillin - Amp e) Vancomycin - Van
Caffeine is used in bilirubin assays to: 1) Stop the diazo reaction 2) Accelerate indirect bilirubin reaction 3) Accelerate direct bilirubin reaction 4) Precipitate proteins 5) Reduce sodium nitrite no references, just homework
Define the following terms: Bactericidal Bacteriostatic Antisepsis
We have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?
Explain the difference between broad-spectrum and narrow-spectrum antibiotics.Give at least two examples of each

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