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Which of the following is true of selective toxicity? O 1) It refers to the process of determining the correct dose of a particular drug 2) To be effective, an antimicrobial agent must be more toxic to the patient than the pathogen O 3) It contributes to antibiotic resistance O 4) It refers to the body's ability to protect the brain and eye O 5) It takes advantage of metabolic and structural differences between host and pathogen

Which of the following is true of selective toxicity? O 1) It refers to the process of determining the correct dose of a particular drug 2) To be effective, an antimicrobial agent must be more toxic to the patient than the pathogen O 3) It contributes to antibiotic resistance O 4) It refers to the body's ability to protect the brain and eye O 5) It takes advantage of metabolic and structural differences between host and pathogen

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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**Understanding Selective Toxicity in Antimicrobial Agents** **Question:** Which of the following is true of selective toxicity? **Options:** 1. It refers to the process of determining the correct dose of a particular drug 2. To be effective, an antimicrobial agent must be more toxic to the patient than the pathogen 3. It contributes to antibiotic resistance 4. It refers to the body's ability to protect the brain and eye 5. It takes advantage of metabolic and structural differences between host and pathogen Selective toxicity is a crucial concept in the development and application of antimicrobial agents. It describes the ability of a drug to target pathogens without harming the host. This is achieved by exploiting metabolic and structural differences between the host and the pathogen, ensuring that the drug selectively targets the harmful microorganisms effectively. In the options given: - Option 1 is incorrect because selective toxicity is not about determining the drug dosage. - Option 2 is incorrect as the antimicrobial agent should be more toxic to the pathogen, not the patient. - Option 3 is incorrect as selective toxicity aims to prevent antibiotic resistance rather than contribute to it. - Option 4 is incorrect; it doesn't relate to the protection of the brain and eye specifically. - Option 5 is correct as it accurately describes the mechanism of selective toxicity.
Transcribed Image Text:**Understanding Selective Toxicity in Antimicrobial Agents** **Question:** Which of the following is true of selective toxicity? **Options:** 1. It refers to the process of determining the correct dose of a particular drug 2. To be effective, an antimicrobial agent must be more toxic to the patient than the pathogen 3. It contributes to antibiotic resistance 4. It refers to the body's ability to protect the brain and eye 5. It takes advantage of metabolic and structural differences between host and pathogen Selective toxicity is a crucial concept in the development and application of antimicrobial agents. It describes the ability of a drug to target pathogens without harming the host. This is achieved by exploiting metabolic and structural differences between the host and the pathogen, ensuring that the drug selectively targets the harmful microorganisms effectively. In the options given: - Option 1 is incorrect because selective toxicity is not about determining the drug dosage. - Option 2 is incorrect as the antimicrobial agent should be more toxic to the pathogen, not the patient. - Option 3 is incorrect as selective toxicity aims to prevent antibiotic resistance rather than contribute to it. - Option 4 is incorrect; it doesn't relate to the protection of the brain and eye specifically. - Option 5 is correct as it accurately describes the mechanism of selective toxicity.
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