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The Figueroa family has a genetically inherited trait called ocular albinism—lack of pigment in the eye—which is caused by a 516-bp deletion in an exon of a single gene. DNA for this gene was amplified from each member of the family and run on the gel shown below. The thickness of the band indicates the relative amount of DNA. Use the pedigree and the gel to determine the most likely mode of inheritance for this disease. a) x-linked dominant b)x-linked recessive c)autosomal dominant d) autosomal recessive e) cant be determined

The Figueroa family has a genetically inherited trait called ocular albinism—lack of pigment in the eye—which is caused by a 516-bp deletion in an exon of a single gene. DNA for this gene was amplified from each member of the family and run on the gel shown below. The thickness of the band indicates the relative amount of DNA. Use the pedigree and the gel to determine the most likely mode of inheritance for this disease. a) x-linked dominant b)x-linked recessive c)autosomal dominant d) autosomal recessive e) cant be determined

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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The Figueroa family has a genetically inherited trait called ocular albinism—lack of pigment in the eye—which is caused by a 516-bp deletion in an exon of a single gene. DNA for this gene was amplified from each member of the family and run on the gel shown below. The thickness of the band indicates the relative amount of DNA. Use the pedigree and the gel to determine the most likely mode of inheritance for this disease.

a) x-linked dominant

b)x-linked recessive

c)autosomal dominant

d) autosomal recessive

e) cant be determined

**Transcription and Explanation for Educational Context** --- **Diagram Explanation** The image consists of two primary sections: a gel electrophoresis result on the left and a pedigree chart on the right. 1. **Gel Electrophoresis Result:** - The gel chart displays DNA fragments for five individuals: Becky, Ben, Jasper, Lyla, and Sam. - Bands represent DNA fragments of varying sizes, visible as blue lines within the gel. - Each lane corresponds to an individual, with different band patterns indicating genetic variations: - Becky: Several bands of varying thickness are visible. - Ben: Displays a pattern of bands distinct from Becky. - Jasper: Features thicker bands in comparison to Becky and Ben. - Lyla: Similarities observed with Jasper's band patterns. - Sam: Band pattern mirrors those observed in Jasper and Lyla, suggesting a genetic link. 2. **Pedigree Chart:** - This chart outlines the familial relationships between the individuals: - Becky and Ben are the parents. - Jasper, Lyla, and Sam are their children. - Shapes indicate gender: circles for females (Becky, Lyla) and squares for males (Ben, Jasper, Sam). Solid maroon indicates affected individuals. - The chart helps visualize the inheritance patterns and potential genetic traits passed down from parents to offspring. **Educational Context** This setup is commonly used in genetics to study hereditary patterns, analyze DNA for specific traits, and understand familial relationships. The gel electrophoresis provides a visual representation of genetic similarities and differences, while the pedigree chart traces inheritance across generations. ---
Transcribed Image Text:**Transcription and Explanation for Educational Context** --- **Diagram Explanation** The image consists of two primary sections: a gel electrophoresis result on the left and a pedigree chart on the right. 1. **Gel Electrophoresis Result:** - The gel chart displays DNA fragments for five individuals: Becky, Ben, Jasper, Lyla, and Sam. - Bands represent DNA fragments of varying sizes, visible as blue lines within the gel. - Each lane corresponds to an individual, with different band patterns indicating genetic variations: - Becky: Several bands of varying thickness are visible. - Ben: Displays a pattern of bands distinct from Becky. - Jasper: Features thicker bands in comparison to Becky and Ben. - Lyla: Similarities observed with Jasper's band patterns. - Sam: Band pattern mirrors those observed in Jasper and Lyla, suggesting a genetic link. 2. **Pedigree Chart:** - This chart outlines the familial relationships between the individuals: - Becky and Ben are the parents. - Jasper, Lyla, and Sam are their children. - Shapes indicate gender: circles for females (Becky, Lyla) and squares for males (Ben, Jasper, Sam). Solid maroon indicates affected individuals. - The chart helps visualize the inheritance patterns and potential genetic traits passed down from parents to offspring. **Educational Context** This setup is commonly used in genetics to study hereditary patterns, analyze DNA for specific traits, and understand familial relationships. The gel electrophoresis provides a visual representation of genetic similarities and differences, while the pedigree chart traces inheritance across generations. ---
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