Answered: Which sample carries a derived X…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

The picture shows a gel of PCR products for the loci SRY, AMELX/Y and ZFX/Y, for three controls and five test human individuals (1-5). Below the gel is the phenotypic sex of each individual, their fertility status, and the number of Barr bodies seen in the nucleus of a somatic cell in each case. The diagram to the right shows the positions of the tested loci on the human sex chromosomes, and also the positions of the PRKX and PRKYgenes.

Which sample carries a derived X chromosome with a translocation due to ectopic crossover between the loci PRKX and PRKY: 46,X,derX,t(X,Y); ?

		1
		2
		3
		4
		5

SRY
AMELY
AMELX
ZFX
ZFY
controls
Barr
bodies?
no
46,XY 46,XX DNA
sex
male female
fertile? yes yes
0 1
1
3
no
1
test samples
2
3
no
f f f
yes
4
no
5
f
no
0 0 2 0
PAR1
PRKX
AMELX
ZFX
46,XY
ol
PAR1
SRY
ZFY
PRKY
AMELY
46,XX
T
||
OO

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