The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the bindin epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1. Epinephrine Plasma Membrane (GDP Beta-2 Adrenergic Receptor GDP G Protein GTP GTP Adenylyl Cyclase ATP Cyclic AMP Protein Kinase A -ATP ADP Phosphorylase Kinase -ATP ADP Glycogen Phosphorylase Glycogen Glucose-1-Phosphate Glycolysis Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells Which of the following statements is true of the Beta-2 Adrenergic Receptor O It is shape specific to epinephrin, the signal molecule O It has the same conformation as adenylyl cyclase O It is not a G protein-linked receptor

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The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of
epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1.
Epinephrine
Plasma
Membrane
Beta-2
Adrenergic
Receptor
(GDP
(GDP) G Protein
GTP
GTP
OIt becomes phosphorylated
Adenylyl
Cyclase
ATP
Cyclic AMP
Protein Kinase A
-ATP
ADP
Phosphorylase Kinase
-ATP
ADP
Glycogen Phosphorylase
Glycogen
Glucose-1-Phosphate
Glycolysis
Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells
Which of the following statements is true of the Beta-2 Adrenergic Receptor
O It is shape specific to epinephrin, the signal molecule
O It has the same conformation as adenylyl cyclase
O It is not a G protein-linked receptor
Transcribed Image Text:The epinephrine signaling pathway plays a role in regulating glucose homeostasis in muscle cells. The signaling pathway is activated by the binding of epinephrine to the beta-2 adrenergic receptor. A simplified model of the epinephrine signaling pathway is represented in Figure 1. Epinephrine Plasma Membrane Beta-2 Adrenergic Receptor (GDP (GDP) G Protein GTP GTP OIt becomes phosphorylated Adenylyl Cyclase ATP Cyclic AMP Protein Kinase A -ATP ADP Phosphorylase Kinase -ATP ADP Glycogen Phosphorylase Glycogen Glucose-1-Phosphate Glycolysis Figure 1. A simplified model of the epinephrine signaling pathway in muscle cells Which of the following statements is true of the Beta-2 Adrenergic Receptor O It is shape specific to epinephrin, the signal molecule O It has the same conformation as adenylyl cyclase O It is not a G protein-linked receptor
An example of feedback is seen in blood clotting. Part of the complex biochemical pathway of clotting is the production of an enzyme that forms the
matrix of the blood clot, but also speeds up the production of still more thrombin. That is, it has a self-catalytic, self-accelerating effect, so that once the
clotting process begins, it runs faster and faster until, ideally, bleeding stops. Thus, this positive feedback loop is part of a larger negative feedback loop,
one that is activated by bleeding and ultimately works to stop the bleeding.
So ultimately in keeping homeostasis, which of the following is true:
This is a positive feedback loop
This is a negative feedback loop
Transcribed Image Text:An example of feedback is seen in blood clotting. Part of the complex biochemical pathway of clotting is the production of an enzyme that forms the matrix of the blood clot, but also speeds up the production of still more thrombin. That is, it has a self-catalytic, self-accelerating effect, so that once the clotting process begins, it runs faster and faster until, ideally, bleeding stops. Thus, this positive feedback loop is part of a larger negative feedback loop, one that is activated by bleeding and ultimately works to stop the bleeding. So ultimately in keeping homeostasis, which of the following is true: This is a positive feedback loop This is a negative feedback loop
Expert Solution
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Signaling pathway

It refers to the series of chemical reactions in which the group of molecules in a cell work together to control a function of the cell. It is the ability of the cell to receive and transmit signals with itself or its environment.

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