signal molecule plasma membrane activated GPCR -activated RTK G protein G protein phospholipase C PI 3-kinase Ras-GEF diacylglycerol phosphorylated inositol adenylyl cyclase IP3 phospholipid Ras Ca2+ MAP kinase kinase kinase cyclic AMP protein kinase 1 calmodulin MAP kinase kinase PKA CaM-kinase PKC MAP kinase Akt kinase ALTERED CELL BEHAVIOR ECB4 EQ16.51/Q16.61 From the information in above Figure, which of the following statements is incorrect, and explain your opinion(explanation)? A. The GPCR and the RTK both activate phospholipase C. B. Activation of either the GPCR or the RTK will lead to activation of transcriptional regulators. C. CaM-kinase is only activated when the GPCR is active and not when the RTK is active. D. Ras is activated only when the RTK is active and not when the GPCR is active.
signal molecule plasma membrane activated GPCR -activated RTK G protein G protein phospholipase C PI 3-kinase Ras-GEF diacylglycerol phosphorylated inositol adenylyl cyclase IP3 phospholipid Ras Ca2+ MAP kinase kinase kinase cyclic AMP protein kinase 1 calmodulin MAP kinase kinase PKA CaM-kinase PKC MAP kinase Akt kinase ALTERED CELL BEHAVIOR ECB4 EQ16.51/Q16.61 From the information in above Figure, which of the following statements is incorrect, and explain your opinion(explanation)? A. The GPCR and the RTK both activate phospholipase C. B. Activation of either the GPCR or the RTK will lead to activation of transcriptional regulators. C. CaM-kinase is only activated when the GPCR is active and not when the RTK is active. D. Ras is activated only when the RTK is active and not when the GPCR is active.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Proteins
We generally tend to think of proteins only from a dietary lens, as a component of what we eat. However, they are among the most important and abundant organic macromolecules in the human body, with diverse structures and functions. Every cell contains thousands and thousands of proteins, each with specific functions. Some help in the formation of cellular membrane or walls, some help the cell to move, others act as messages or signals and flow seamlessly from one cell to another, carrying information.
Protein Expression
The method by which living organisms synthesize proteins and further modify and regulate them is called protein expression. Protein expression plays a significant role in several types of research and is highly utilized in molecular biology, biochemistry, and protein research laboratories.
Question
Transcribed Image Text:2. Following Figure shows that intracellular signaling
pathways can be highly interconnected?
signal molecule
plasma membrane
activated GPCR
activated RTK
G protein
G protein →
phospholipase C
PI 3-kinase
Ras-GEF
phosphorylated
inositol
phospholipid
adenylyl cyclase
IP3
diacylglycerol
Ras
Ca+
MAP kinase kinase kinase
cyclic AMP
protein kinase 1
calmodulin
MAP kinase kinase
PKA
CaM-kinase
РКС
MAP kinase
Akt kinase
ALTERED CELL BEHAVIOR
ECB4 EQ16.51/Q16.61
From the information in above Figure, which of the
following statements is incorrect, and explain your
opinion(explanation)?
A. The GPCR and the RTK both activate
phospholipase C.
B. Activation of either the GPCR or the RTK will
lead to activation of transcriptional regulators.
C. CaM-kinase is only activated when the GPCR is
active and not when the RTK is active.
D. Ras is activated only when the RTK is active and
not when the GPCR is active.
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