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NORMAL SIGNALING PATHWAY REQUIRES Ras AND TWO PROTEINS, X AND Y signal molecule active Ras protein CYTOSOL GTP active receptor active signaling protein X tyrosine kinase The figure below shows how normal signaling works with a Ras protein acting downstream of an RTK. You examine a cell line with a constitutively active Ras protein. Signaling in this cell line can be turned off by adding a drug that -mitogen active Ras protein CYTOSOL GTP active signaling active receptor active signaling protein X protein Y tyrosine kinase | CELL DIVISON O a) prevents the ligand from binding to the RTK O b) prevents protein Y from interacting with its target O c) increases the affinity of protein Y and Ras O d) increases the activity of protein Y O e) prevents protein X from activating Ras

NORMAL SIGNALING PATHWAY REQUIRES Ras AND TWO PROTEINS, X AND Y signal molecule active Ras protein CYTOSOL GTP active receptor active signaling protein X tyrosine kinase The figure below shows how normal signaling works with a Ras protein acting downstream of an RTK. You examine a cell line with a constitutively active Ras protein. Signaling in this cell line can be turned off by adding a drug that -mitogen active Ras protein CYTOSOL GTP active signaling active receptor active signaling protein X protein Y tyrosine kinase | CELL DIVISON O a) prevents the ligand from binding to the RTK O b) prevents protein Y from interacting with its target O c) increases the affinity of protein Y and Ras O d) increases the activity of protein Y O e) prevents protein X from activating Ras

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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NORMAL SIGNALING PATHWAY REQUIRES Ras AND TWO PROTEINS, X AND Y - signal molecule active Ras protein CYTOSOL GTP active receptor active signaling protein X tyrosine kinase The figure below shows how normal signaling works with a Ras protein acting downstream of an RTK. You examine a cell line with a constitutively active Ras protein. Signaling in this cell line can be turned off by adding a drug that mitogen active Ras protein CYTOSOL GTP active signaling active receptor active signaling protein X protein Y tyrosine kinase CELL DIVISON a) prevents the ligand from binding to the RTK b) prevents protein Y from interacting with its target c) increases the affinity of protein Y and Ras d) increases the activity of protein Y e) prevents protein X from activating Ras
Transcribed Image Text:NORMAL SIGNALING PATHWAY REQUIRES Ras AND TWO PROTEINS, X AND Y - signal molecule active Ras protein CYTOSOL GTP active receptor active signaling protein X tyrosine kinase The figure below shows how normal signaling works with a Ras protein acting downstream of an RTK. You examine a cell line with a constitutively active Ras protein. Signaling in this cell line can be turned off by adding a drug that mitogen active Ras protein CYTOSOL GTP active signaling active receptor active signaling protein X protein Y tyrosine kinase CELL DIVISON a) prevents the ligand from binding to the RTK b) prevents protein Y from interacting with its target c) increases the affinity of protein Y and Ras d) increases the activity of protein Y e) prevents protein X from activating Ras
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