If neither Viagra or ginseng works to fix the cat's problem,  PKG would be considered “broken” in this signalling pathway, Why?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question

If neither Viagra or ginseng works to fix the cat's problem,  PKG would be considered “broken” in this signalling pathway, Why?

LOCALLY PRODUCED
NITRIC OXIDE
Ca2*
EXPORT
PDE5
INHIBITORS
Ca2+
SEQUESTRATION,
Ca2+
RELEASE
5'-GMP
GC
P'Lamban
GTP
IP3
Receptor
Ca2+
PDE5
KCGMP
PKG
MLC P'tase
MLC
MLC-P
MLCK
RELAXATION
CONTRACTION
BK K* CHANNEL
Transcribed Image Text:LOCALLY PRODUCED NITRIC OXIDE Ca2* EXPORT PDE5 INHIBITORS Ca2+ SEQUESTRATION, Ca2+ RELEASE 5'-GMP GC P'Lamban GTP IP3 Receptor Ca2+ PDE5 KCGMP PKG MLC P'tase MLC MLC-P MLCK RELAXATION CONTRACTION BK K* CHANNEL
Smooth Muscle
Cell
Nitroglycerin
Guanylyl Cyclase
(inactive)
Nitric Oxide .
GTP
N:O-Guanylyl Cyclase
(active)
Nitric Oxide
CGMP
Inactive PKG
(N:O)
fCitrulline
Activated PKG
ATP
Nitric
Oxide
Synthase
Proteins
Phospho-Proteins
Ca2
Сам
Lowering of Ca²*
Desensitization to Ca2+
L-Arginine
Endothelial
Or Neuronal
Cell
Relaxation
Transcribed Image Text:Smooth Muscle Cell Nitroglycerin Guanylyl Cyclase (inactive) Nitric Oxide . GTP N:O-Guanylyl Cyclase (active) Nitric Oxide CGMP Inactive PKG (N:O) fCitrulline Activated PKG ATP Nitric Oxide Synthase Proteins Phospho-Proteins Ca2 Сам Lowering of Ca²* Desensitization to Ca2+ L-Arginine Endothelial Or Neuronal Cell Relaxation
Expert Solution
steps

Step by step

Solved in 2 steps with 1 images

Blurred answer
Knowledge Booster
Cell signaling
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education