Recently, a Gα q-coupled receptor was discovered that mediates at least some of the many activities of estrogen.  At the time, this discovery generated considerable controversy, as it ran counter to what was then the understanding of how steroid hormone signaling worked.  Which of the following observations might have led the investigators to suspect the existence of this newly discovered receptor?     A. Activities of estrogen apparent less than 1 minute after application of the hormone   B. The growth promoting activity of estrogen   C. The presence of estrogen nuclear receptors in cells not previously known to respond to the hormone   D. Estrogen is found in much higher concentrations in adult women than adult men   E. Uptake of estrogen by target cells

Q: How can you tell epinephrine is a peptide hormone and not a steroid one by looking at the picture?

A: hormones are chemicals which are secreted by specialized organs in small quantities to produce…

Q: Release of glucose into the bloodstream from cells in the liver can be initiated by epinephrine…

A: Glucose is a simple sugar and the primary source of energy for most living organisms. It is a…

Q: 2) Indicate by writing “yes” or “no” whether amplification of a signal could occur at the particular…

A: An essential mechanism that permits cells to react to alterations in their environment is signal…

Q: In relation to Cushing’s Syndrome, a method that some scientists have used to treat the disease is…

A: Biochemical receptors are protein molecules that get activated when a ligand like drugs, or hormones…

Q: What are the roles of the following signaling molecules in the glucagon pathway:  a. Ligand b.…

A: ANSWER : a. Ligand: A ligand is a molecule which binds with another certain molecule by forming a…

Q: Three membrane receptor proteins bind tightly to a hormone. Based on the data in the table below,…

A: Protein can bind to substrate/hormones with different affinities. The smaller the KD value, the…

Q: Mutations were introduced into a type I receptor of steroid hormone X. Two classes of mutants were…

A: Gene expression under the hormonal influence means that the when the hormone binds to its receptor…

Q: What is the role of lipidated proteins in G-protein-coupled receptors during signal transduction?

A: G-protein coupled receptor refers to the cell surface receptor that recognizes molecules (ligand)…

Q: Please identify the incorrect statement about hormone signaling: A) Cystolic receptors bind to…

A: The signaling molecules fall into 2 groups  Hydrophilic and Hydrophobic molecules. Hydrophilic…

Q: Aberrant signaling through the EGF receptor signal transduction pathway drives many forms of breast…

A: Cell signaling is mediated by a ligand (usually a hormone but could be other molecules too) binding…

Q: Estrogen receptor antagonists inhibit tumors by: 1) blocking estrogen binding to receptors 2)…

A: Antiestrogens are a class of medications that stop estrogens like estradiol from mediating their…

Q: Which of the following would result in an INCREASE in BLOOD glucose levels ? choose all of the…

A: Introduction :- Glucose is the final product of digestion of food , that we intake . After complete…

Q: Why is it regarded extraordinary that a monomeric hormone may attach to two identical receptor…

A: Some receptors dimerize upon binding to their ligand. Ligand binding to its receptor can cause…

Q: What is the purpose of having a sex hormone binding protein within the blood stream? What is the…

A: Hi! Thank you for your question. But as you have posted multiple questions and have not mentioned…

Q: Progesterone is a steroid hormone that is produced by the placenta during pregnancy. Based on its…

A: Progesterone is a steroid hormone present in females. It is produced during pregnancy. The hormone…

Q: In studies trying to understand the regulation of hormone-sensitive adenylate cyclase, it was…

A: Understanding the intricate regulation of hormone-sensitive adenylate cyclase is pivotal in…

Q: Why is the fact that a monomeric hormone binds simultaneously to two identical receptor molecules,…

A: The growth-hormone receptor contains 638 amino acids, divided into a extracellular domain of 250…

Q: If you are provided with a CHO cell line expressing an adrenergic receptor, how could you…

A: Introduction :- Chinese hamster ovary (CHO) cells are epithelial cell lines derived from the ovaries…

Q: Explain how mutations in the following proteins might result in either loss of responsiveness to a…

A: A mutation refers to the alteration in the nucleotide sequence of DNA. It is caused by physical,…

Q: You are studying a drug that affects a cAMP signalling pathway that is normally initiated when a…

A: GPCRs are present in all eukaryotes. It is the largest family of cell surface receptors that…

Q: Which of the following is not a true statement? A.) steroid and thyroid hormone signaling would be…

A: Hormones are chemical messengers produced and secreted by the endocrine glands. Hormones regulate…

Q: GTP is an important high-energy molecule that facilitates the activation of many cellular sig- nal…

A: GTP (guanosine triphosphate) is an important energy-carrying molecule used in a variety of metabolic…

Q: The one i have to use to answer these questions are Prolactin please :)

A: Approach to solving the question:Understand the structure and function of prolactin and its…

Q: Label the molecules in this figure showing how IP3 and DAG function as second messengers. Note: not…

A: Small molecules such as ions or proteins capable of transmitting signals to target molecules via…

Q: The name of the enzyme that recognizes phosphotyrosines on an activated tyrosine kinase receptor in…

A: Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for molecules such as…

Q: Beta-blockers are used to treat cardiovascular disorders because they are antagonists at…

A: Beta blockers are used as medications that reduce blood pressure. These compounds can prevent…

Cancer Therapy