The CTCF protein is involved in the regulation of the Igf2-H19 gene cluster. Which of the following statements relating to this is TRUE? CTCF binds only to the methylated imprinting control region (ICR) CTCF activates the enhancer of the Igf2 gene CTCF binds only to the ICR on the maternal copy of the chromosome Two of the above All of the above
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
The CTCF protein is involved in the regulation of the Igf2-H19 gene cluster. Which of the following statements relating to this is TRUE?
- CTCF binds only to the methylated imprinting control region (ICR)
- CTCF activates the enhancer of the Igf2 gene
- CTCF binds only to the ICR on the maternal copy of the chromosome
- Two of the above
- All of the above
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