Answered: TABLE Q5-1 Frequencies of mutant cells…

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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To determine the reproducibility of mutation fre-
quency measurements, you do the following experiment.
You inoculate each of 10 cultures with a single E. coli bac-
terium, allow the cultures to grow until each contains 106
cells, and then measure the number of cells in each culture
that carry a mutation in your gene of interest. You were so
surprised by the initial results that you repeated the experi-
ment to confirm them. Both sets of results display the same
extreme variability, as shown in Table Q5–1. Assuming that
the rate of mutation is constant, why do you suppose there
is so much variation in the frequencies of mutant cells in
different cultures?

TABLE Q5-1 Frequencies of mutant cells in multiple
cultures (Problem 5–6)
Culture (mutant cells/106 cells)
Experiment
1 2 3 4 5 6 7 8
9 10
4 0 257 1 0 o
2 32
2
2
128 0
1 4 0
O 66
2
LO

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