17. Spinocerebellar Ataxia Type 2 is a trinucleotide expansion disorder. Normal individuals have up to 32 trinucleotide repeats, and individuals with 33 or more repeats develop symptoms. You have a pair of 20-nucleotide-long PCR primers for genotyping. The 5' end of each primer begins 25 nucleotides outside of the repeat. How long a PCR fragment would be indicative of the shortest product found in someone likely to develop the disease? a-83 b.99 32 Sheal they 33+-diseased C. 139 d. 149 ts e. 189 33 X 3 X 3 99+50+40 99 1 +

Human Anatomy & Physiology (11th Edition)
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Chapter1: The Human Body: An Orientation
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17. Spinocerebellar Ataxia Type 2 is a trinucleotide expansion disorder. Normal individuals have up to
32 trinucleotide repeats, and individuals with 33 or more repeats develop symptoms. You have a pair
of 20-nucleotide-long PCR primers for genotyping. The 5' end of each primer begins 25 nucleotides
outside of the repeat. How long a PCR fragment would be indicative of the shortest product found in
someone likely to develop the disease?
a-83-
энеакти
b. 99
32
33 + diseased.
139
99
d. 149
tso
99 +50+40
33 X 3
X 3
e. 189
99
common in the human genome?
190
+4
18
Transcribed Image Text:17. Spinocerebellar Ataxia Type 2 is a trinucleotide expansion disorder. Normal individuals have up to 32 trinucleotide repeats, and individuals with 33 or more repeats develop symptoms. You have a pair of 20-nucleotide-long PCR primers for genotyping. The 5' end of each primer begins 25 nucleotides outside of the repeat. How long a PCR fragment would be indicative of the shortest product found in someone likely to develop the disease? a-83- энеакти b. 99 32 33 + diseased. 139 99 d. 149 tso 99 +50+40 33 X 3 X 3 e. 189 99 common in the human genome? 190 +4 18
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