Standard free energy changes (AG) of hydrolysis of ATP and phosphocreatine (PCr) are -30 and -43 kJ/mol respectively. Predict whether creatine kinase will operate in the direction of ATP synthesis or PCr synthesis at 25°C when [ATP]; = 4.0 mM, [ADP]: = 0.15 mM, [PCr]; = 2.5 mM, and [Cr]; = 1.0 %3D mM. (RT=2.5 kJ/mol) Creatine kinase PCr + ADP Cr + ATP
Standard free energy changes (AG) of hydrolysis of ATP and phosphocreatine (PCr) are -30 and -43 kJ/mol respectively. Predict whether creatine kinase will operate in the direction of ATP synthesis or PCr synthesis at 25°C when [ATP]; = 4.0 mM, [ADP]: = 0.15 mM, [PCr]; = 2.5 mM, and [Cr]; = 1.0 %3D mM. (RT=2.5 kJ/mol) Creatine kinase PCr + ADP Cr + ATP
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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![1.
Standard free energy changes (AG) of hydrolysis of ATP and phosphocreatine (PCr) are -30 and-43
kJ/mol respectively. Predict whether creatine kinase will operate in the direction of ATP synthesis or
PCr synthesis at 25°C when [ATP]; = 4.0 mM, [ADP]; = 0.15 mM, [PCr] = 2.5 mM, and [Cr] = 1.0
mM.
!!
(RT= 2.5 kJ/mol)
Creatine
kinase
PCr + ADP
Cr + ATP](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Ffaf0b2a8-4042-45f2-9e5b-64e96a6ac0aa%2F1cef6f9f-4d10-454e-807e-e0787c258697%2Fxhwumc_processed.jpeg&w=3840&q=75)
Transcribed Image Text:1.
Standard free energy changes (AG) of hydrolysis of ATP and phosphocreatine (PCr) are -30 and-43
kJ/mol respectively. Predict whether creatine kinase will operate in the direction of ATP synthesis or
PCr synthesis at 25°C when [ATP]; = 4.0 mM, [ADP]; = 0.15 mM, [PCr] = 2.5 mM, and [Cr] = 1.0
mM.
!!
(RT= 2.5 kJ/mol)
Creatine
kinase
PCr + ADP
Cr + ATP
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